Autosomal Dominant Polycystic Kidney Disease in which the Polycystic Liver Volume Was Reduced by Rigorous Blood Pressure Control

Polycystic liver disease (PLD) is the most common extrarenal manifestation of autosomal dominant polycystic kidney disease (ADPKD). However, current treatments for PLD are only supportive. We experienced a case of enlarged kidneys and liver in a 53-year-old Japanese man with ADPKD who was on hemodia...

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Published in:Internal Medicine 2022/01/01, Vol.61(1), pp.49-52
Main Authors: Suwabe, Tatsuya, Ubara, Yoshifumi, Ikuma, Daisuke, Mizuno, Hiroki, Hayami, Noriko, Yamanouchi, Masayuki, Sawa, Naoki
Format: Article
Language:English
Subjects:
ADPKD
Blood Pressure
Case Report
Cysts - diagnostic imaging
Embolization
Hemodialysis
Humans
Internal medicine
Kidney - diagnostic imaging
Kidney diseases
Liver
Liver diseases
Liver Diseases - diagnostic imaging
Liver Diseases - therapy
Male
Middle Aged
PLD
Polycystic kidney
polycystic kidney disease
Polycystic Kidney, Autosomal Dominant - complications
Polycystic Kidney, Autosomal Dominant - therapy
polycystic liver disease
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Summary:Polycystic liver disease (PLD) is the most common extrarenal manifestation of autosomal dominant polycystic kidney disease (ADPKD). However, current treatments for PLD are only supportive. We experienced a case of enlarged kidneys and liver in a 53-year-old Japanese man with ADPKD who was on hemodialysis. He underwent renal transcatheter arterial embolization (TAE) for enlarged kidneys. His blood pressure (BP) decreased after renal TAE, and his liver volume decreased from 5,259 mL to 4,647 mL (11.6% reduction) within 1 year after renal TAE. This case suggests that rigorous blood pressure control may be beneficial for ameliorating enlarged PLD.
ISSN:0918-2918
1349-7235
DOI:10.2169/internalmedicine.7441-21