Decrease in Serum Adiponectin Levels in Response to Treatment Predicts Good Prognosis in Acute Decompensated Heart Failure

J Clin Hypertens (Greenwich). Adiponectin is a cardioprotective adipocytokine. Serum adiponectin concentration decreases in patients who are obese but increases in patients with chronic heart failure (CHF). The aim of this study was to explore the temporal changes in serum adiponectin concentration...

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Published in:The journal of clinical hypertension (Greenwich, Conn.) Conn.), 2010-11, Vol.12 (11), p.900-904
Main Authors: Matsumoto, Mika, Lee‐Kawabata, Masaaki, Tsujino, Takeshi, Naito, Yoshiro, Ezumi, Akira, Sakoda, Tsuyoshi, Ohyanagi, Mitsumasa, Shimomura, Iichiro, Masuyama, Tohru
Format: Article
Language:English
Subjects:
Acute Disease
Adiponectin - blood
Adipose Tissue - drug effects
Adipose Tissue - metabolism
Aged
Aged, 80 and over
Female
Follow-Up Studies
Heart Failure - drug therapy
Heart Failure - metabolism
Heart Failure - physiopathology
Hospitalization
Humans
Male
Middle Aged
Mortality
Original Papers
Predictive Value of Tests
Prognosis
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Summary:J Clin Hypertens (Greenwich). Adiponectin is a cardioprotective adipocytokine. Serum adiponectin concentration decreases in patients who are obese but increases in patients with chronic heart failure (CHF). The aim of this study was to explore the temporal changes in serum adiponectin concentration following treatment for acute decompensated heart failure (ADHF). Serum adiponectin was measured on admission and at discharge in 95 patients who were admitted to our hospital with ADHF. Ten patients without heart failure (HF) served as controls. Serum adiponectin concentration was higher on admission in HF patients than in the controls (22.6±13.3 μg/mL vs 9.3±3.9 μg/mL, P
ISSN:1524-6175
1751-7176
DOI:10.1111/j.1751-7176.2010.00368.x