Correlates of Biochemical Markers of Bone turnover among Post-Menopausal Women

Bone turnover leading to osteoporosis and poor quality of life is common during post-menopausal period. Study of bone turnover markers that contribute to non-invasive assessment of bone-metabolic disorders holds an important area of research in low income country like Nepal. This study aimed to exam...

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Bibliographic Details
Published in:Journal of Nepal Medical Association 2018-07, Vol.56 (212), p.754-758
Main Authors: Khadka, Bikram, Tiwari, Mohan Lal, Gautam, Ravi, Timalsina, Binod, Pathak, Nandu Prasad, Kharel, Krishna, Sharma, Shanta, Acharya, Dilaram
Format: Article
Language:English
Subjects:
Adult
Alkaline Phosphatase - blood
Biomarkers - blood
Bone and Bones - metabolism
Calcium - blood
Cross-Sectional Studies
Female
Humans
Middle Aged
Original
Osteoporosis, Postmenopausal - blood
Osteoporosis, Postmenopausal - metabolism
Phosphorus - blood
Vitamin D - blood
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Summary:Bone turnover leading to osteoporosis and poor quality of life is common during post-menopausal period. Study of bone turnover markers that contribute to non-invasive assessment of bone-metabolic disorders holds an important area of research in low income country like Nepal. This study aimed to examine the correlates of bone turnover markers in post-menopausal women in tertiary level of health care center of Nepal. A hospital-based cross-sectional study conducted during the period of November 2016 to December 2017 among 354 women. Blood samples for calcium, inorganic phosphorus, alkaline phosphatase and vitamin D were collected and analyzed using a validated and calibrated tools. Data were analyzed using Statistical Package for the Social Sciences software version 20. Mean±Standard deviation of age of post-menopausal women was significantly higher compared to pre-menopausal women (post-menopausal women, (57.98±8.08) vs. pre-menopausal, (31.35±5.83), (P
ISSN:0028-2715
1815-672X
DOI:10.31729/jnma.3604