Infection and pathogenesis of the Delta variant of SARS-CoV-2 in Rhesus macaque

•Delta variant of SARS-CoV-2 can effectively infect the Rhesus macaque.•Delta variant grows faster than the early strain isolated from Wuhan in late 2019.•Shedding pattern, viral load and disease severity of Delta variant are similar to the early strain isolated from Wuhan.•This study supports the a...

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Bibliographic Details
Published in:Virologica Sinica 2022-04, Vol.37 (2), p.299-302
Main Authors: Gao, Ge, Hu, Xue, Zhou, Yiwu, Rao, Juhong, Zhang, Xiaoyu, Peng, Yun, Zhao, Jiaxuan, Yao, Yanfeng, Liu, Kunpeng, Liang, Mengying, Liu, Hang, Deng, Fei, Xia, Han, Shan, Chao, Yuan, Zhiming
Format: Article
Language:English
Subjects:
Animals
COVID-19
Letter
Macaca mulatta
SARS-CoV-2 - genetics
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Summary:•Delta variant of SARS-CoV-2 can effectively infect the Rhesus macaque.•Delta variant grows faster than the early strain isolated from Wuhan in late 2019.•Shedding pattern, viral load and disease severity of Delta variant are similar to the early strain isolated from Wuhan.•This study supports the attributed rapid disease spread of the Delta variant.
ISSN:1995-820X
1674-0769
1995-820X
DOI:10.1016/j.virs.2022.02.001