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Minimal Information about MHC Multimers (MIAMM)

With the goal of improving the reproducibility and annotatability of MHC multimer reagent data, we present the establishment of a new data standard: Minimal Information about MHC Multimers (https://miamm.lji.org/). Multimers are engineered reagents composed of a ligand and a MHC, which can be repres...

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Published in:The Journal of immunology (1950) 2022-02, Vol.208 (3), p.531-537
Main Authors: Vita, Randi, Mody, Apurva, Overton, James A, Buus, Soren, Haley, Stephen T, Sette, Alessandro, Mallajosyula, Vamsee, Davis, Mark M, Long, Dale L, Willis, Richard A, Peters, Bjoern, Altman, John D
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container_title The Journal of immunology (1950)
container_volume 208
creator Vita, Randi
Mody, Apurva
Overton, James A
Buus, Soren
Haley, Stephen T
Sette, Alessandro
Mallajosyula, Vamsee
Davis, Mark M
Long, Dale L
Willis, Richard A
Peters, Bjoern
Altman, John D
description With the goal of improving the reproducibility and annotatability of MHC multimer reagent data, we present the establishment of a new data standard: Minimal Information about MHC Multimers (https://miamm.lji.org/). Multimers are engineered reagents composed of a ligand and a MHC, which can be represented in a standardized format using ontology terminology. We provide an online Web site to host the details of the standard, as well as a validation tool to assist with the adoption of the standard. We hope that this publication will bring increased awareness of Minimal Information about MHC Multimers and drive acceptance, ultimately improving the quality and documentation of multimer data in the scientific literature.
doi_str_mv 10.4049/jimmunol.2100961
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subjects HLA-A Antigens - immunology
Humans
Indicators and Reagents - chemistry
Internet
Major Histocompatibility Complex - genetics
Multiprotein Complexes - chemistry
T-Lymphocytes - immunology
title Minimal Information about MHC Multimers (MIAMM)
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