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Evaluating the Oral-Health-Related Quality of Life of Oral Submucous Fibrosis Patients before and after Treatment Using the OHIP-14 Tool

The objective of the present study was to assess the oral-health-related quality of life (OHRQoL) of oral submucous fibrosis (OSMF) patients before and after standard treatment. A convenient sampling technique was used to recruit the clinically diagnosed patients of OSMF (n = 130). Based on the medi...

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Published in:International journal of environmental research and public health 2022-02, Vol.19 (3), p.1821
Main Authors: Memon, Abdul Bari, Rahman, Aneela Atta Ur, Channar, Kashif Ali, Zafar, Muhammad Sohail, Kumar, Naresh
Format: Article
Language:English
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Summary:The objective of the present study was to assess the oral-health-related quality of life (OHRQoL) of oral submucous fibrosis (OSMF) patients before and after standard treatment. A convenient sampling technique was used to recruit the clinically diagnosed patients of OSMF (n = 130). Based on the medical treatment, the patients were randomly divided into two study groups (group A and B). The group A patients received submucosal intralesional injections of dexamethasone (2 mL; 4 gm/mL), while group B patients received hyaluronidase (1500 IU). Both the group A and B patients received respective medical therapy biweekly for a period of five weeks. At the follow up visit (6 months), the impact of treatment on OHRQoL was assessed using the Oral Health Impact Profile-14 (OHIP-14). Data were analyzed by a chi-square test for quantitative variables and an independent -test for qualitative variables. The comparison of all clinical parameters before and after treatment was performed by a paired -test. The results after treatment showed that there was a significant improvement in all domains of OHIP-14 ( = 0.001) except psychological disability ( = 0.243). In addition, the OHRQoL of patients was significantly improved following the treatment.
ISSN:1660-4601
1661-7827
1660-4601
DOI:10.3390/ijerph19031821