RAFT-Based Polymers for Click Reactions

The parallel development of reversible deactivation radical polymerization and click reaction concepts significantly enriches the toolbox of synthetic polymer chemistry. The synergistic effect of combining these approaches manifests itself in a growth of interest to the design of well-defined functi...

Full description

Saved in:
Bibliographic Details
Published in:Polymers 2022-01, Vol.14 (3), p.570
Main Authors: Chernikova, Elena V, Kudryavtsev, Yaroslav V
Format: Article
Language:English
Subjects:
Addition polymerization
Antifouling coatings
Biomolecules
Chain transfer
Chemical reactions
Chemistry
Conjugation
Copolymers
Corrosion prevention
Macromolecules
Nanoparticles
Polymer blends
Polymer chemistry
Polymerization
Polymers
Review
Self-assembly
Synergistic effect
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The parallel development of reversible deactivation radical polymerization and click reaction concepts significantly enriches the toolbox of synthetic polymer chemistry. The synergistic effect of combining these approaches manifests itself in a growth of interest to the design of well-defined functional polymers and their controlled conjugation with biomolecules, drugs, and inorganic surfaces. In this review, we discuss the results obtained with reversible addition-fragmentation chain transfer (RAFT) polymerization and different types of click reactions on low- and high-molar-mass reactants. Our classification of literature sources is based on the typical structure of macromolecules produced by the RAFT technique. The review addresses click reactions, immediate or preceded by a modification of another type, on the leaving and stabilizing groups inherited by a growing macromolecule from the chain transfer agent, as well as on the side groups coming from monomers entering the polymerization process. Architecture and self-assembling properties of the resulting polymers are briefly discussed with regard to their potential functional applications, which include drug delivery, protein recognition, anti-fouling and anti-corrosion coatings, the compatibilization of polymer blends, the modification of fillers to increase their dispersibility in polymer matrices, etc.
ISSN:2073-4360
2073-4360
DOI:10.3390/polym14030570