Preparation and Characterization of Antibacterial Films with Eggshell-Membrane Biopolymers Incorporated with Chitosan and Plant Extracts

A series of films containing chitosan (CS), eggshell membrane (ESM), soluble eggshell membrane (SEP), and plant extracts from and were prepared with varying concentrations and compositions. These novel films were characterized extensively with respect to film thickness and uniformity, solution absor...

Full description

Saved in:
Bibliographic Details
Published in:Polymers 2022-01, Vol.14 (3), p.383
Main Authors: Webb, Brian Cameron Wooding, Rafferty, Steven, Vreugdenhil, Andrew James
Format: Article
Language:English
Subjects:
Absorption
Biopolymers
Chemical bonds
Chitosan
Collagen
Costs
Degradation
E coli
Fibroblasts
Film thickness
Gene expression
Glycerol
Incorporation
Infections
Lysozyme
Membranes
Spectrum analysis
Wound healing
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A series of films containing chitosan (CS), eggshell membrane (ESM), soluble eggshell membrane (SEP), and plant extracts from and were prepared with varying concentrations and compositions. These novel films were characterized extensively with respect to film thickness and uniformity, solution absorption, degradation, microenvironmental pH, and antibacterial properties. All the films were flexible with appropriate mechanical stability. After 48 h of soaking in a lysozyme solution, all the films degraded 64 ± 4%, which would be expected to allow for the release of the plant extracts. The plant extracts on their own showed a pH of approximately 4, with the blended films having microenvironmental pHs from approximately 6.4-7.0, which would be expected to promote wound healing. A CS-ESM-SEP film with 5% of each plant extract inhibited almost all growth in liquid cultures and had no detriments to fluid absorption. Fluid absorption was approximately 100-150% by weight for all the films. The incorporation of SEP and plant extracts to a CS-ESM film provides a promising and novel method for the incorporation of SEP and antibacterial agents in a film with no detriment to wound fluid absorption or film degradation.
ISSN:2073-4360
2073-4360
DOI:10.3390/polym14030383