Mucoepidermoid carcinoma: A retrospective clinicopathologic study of 25 cases

Background: Salivary gland tumors are rare and clinically represent a diverse group of neoplasms among which mucoepidermoid carcinoma (MEC) is a relatively common salivary gland tumor with varying potential for aggressive behavior. The purpose of the study was aimed at to analyze the relative freque...

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Published in:Journal of oral and maxillofacial pathology : JOMFP 2021-09, Vol.25 (3), p.490-493
Main Authors: Jeergal, Prabhakar, Karim Namazi, Nasim, Patil, Shashi, Kochar, Anagha, Sohoni, Rohan, Bussari, Smita
Format: Article
Language:English
Subjects:
Cancer
Carcinoma
Epidemiology
Exocrine glands
Geographical distribution
Health aspects
Oral cancer
Original
Palate
Parotid gland
Salivary gland
Tumors
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Summary:Background: Salivary gland tumors are rare and clinically represent a diverse group of neoplasms among which mucoepidermoid carcinoma (MEC) is a relatively common salivary gland tumor with varying potential for aggressive behavior. The purpose of the study was aimed at to analyze the relative frequency and correlate with age, sex, anatomical site and histological grade of MEC and compare the findings with epidemiological data from different geographic locations. Materials and Methods: Twenty-five cases diagnosed with MEC during the period June 1985 to June 2004 (19 years) were retrieved from the Department of Pathology, Government Medical College and Hospital, Ambajogai, and clinical data were recorded and reviewed histopathologically. Results: The relative frequency of MEC was 13.15%. Low-grade MEC (44%) was the most common, followed by intermediate-grade MEC (36%) and high-grade MEC (20%). The mean age for occurrence of MEC was 44.28 ± 13.29 years. MEC was predominant in females (60%) than males (40%). Thus, the overall female-male ratio was 1.5:1. Among minor salivary glands, palate (48%) was the most common site, and among major salivary glands, parotid gland (16%) was the common site. Conclusion: Comparing the present data with previous studies on MEC, one may infer that some demographic characteristics and the predominance vary in different geographic regions. Analysis of the distribution and particular features of MEC in a specific population helps in establishment of appropriate treatment.
ISSN:0973-029X
1998-393X
DOI:10.4103/jomfp.jomfp_67_21