Pulmonary Alveolar Proteinosis with Severe Respiratory Failure Improved by Segmental Lung Lavage with Fiberoptic Bronchoscopy under General Anesthesia

Pulmonary alveolar proteinosis (PAP) is a rare disorder in which lipoproteinaceous materials accumulate in the alveolar compartments. A 72-year-old man was diagnosed with autoimmune PAP with severe respiratory failure. We decided to perform segmental lung lavage (SLL) with fiberoptic bronchoscopy un...

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Bibliographic Details
Published in:Internal Medicine 2022/02/01, Vol.61(3), pp.389-393
Main Authors: Matsumoto, Yu, Masuda, Takeshi, Takahashi, Tatsuki, Hashimoto, Kaori, Yamaguchi, Kakuhiro, Sakamoto, Shinjiro, Horimasu, Yasushi, Nakashima, Taku, Miyamoto, Shintaro, Iwamoto, Hiroshi, Ohshimo, Shinichiro, Fujitaka, Kazunori, Yamasaki, Masahiro, Hamada, Hironobu, Hattori, Noboru
Format: Article
Language:English
Subjects:
Aged
Alveoli
Anesthesia
Anesthesia, General
Bronchoalveolar Lavage
Bronchoscopy
Case Report
Computed tomography
fiberoptic bronchoscopy
General anesthesia
Humans
Internal medicine
Lavage
Male
pulmonary alveolar proteinosis
Pulmonary Alveolar Proteinosis - diagnosis
Pulmonary Alveolar Proteinosis - diagnostic imaging
Respiratory Insufficiency - etiology
Respiratory Insufficiency - therapy
segmental lung lavage
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Summary:Pulmonary alveolar proteinosis (PAP) is a rare disorder in which lipoproteinaceous materials accumulate in the alveolar compartments. A 72-year-old man was diagnosed with autoimmune PAP with severe respiratory failure. We decided to perform segmental lung lavage (SLL) with fiberoptic bronchoscopy under general anesthesia. If improvement was not significant, whole-lung lavage (WLL) would be done. SLL improved the respiratory failure and computed tomography findings. This case showed improvement in not only the area where lavage was done but also the non-lavaged area. SLL with fiberoptic bronchoscopy under general anesthesia might be an appropriate treatment option for patients with severe PAP.
ISSN:0918-2918
1349-7235
DOI:10.2169/internalmedicine.7432-21