Multifocal Electroretinogram Alterations after Intravitreal Ranibizumab Treatment in Diabetic Macular Edema

To assess multifocal electroretinogram (mf-ERG) values in patients with diabetic macular edema (DME) who were treated with intravitreal ranibizumab (IVR). Thirty eyes of patients with DME, who underwent three consecutive monthly injections of IVR and as required thereafter, were evaluated. Best corr...

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Bibliographic Details
Published in:Beyoglu eye journal 2022, Vol.7 (1), p.39-46
Main Authors: Kaderli, Sema Tamer, Hazirolan, Dicle, Uney, Guner, Kaderli, Ahmet, Unlu, Nurten, Acar, Mehmet Akif, Ornek, Firdevs
Format: Article
Language:English
Subjects:
Cysts
Diabetes
Edema
Original
Tomography
Visual acuity
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Summary:To assess multifocal electroretinogram (mf-ERG) values in patients with diabetic macular edema (DME) who were treated with intravitreal ranibizumab (IVR). Thirty eyes of patients with DME, who underwent three consecutive monthly injections of IVR and as required thereafter, were evaluated. Best corrected visual acuity (BCVA) (log MAR), optical coherence tomography (OCT) features [diameters of cyst and subretinal fluid, hyperreflective dots (HRDs)], and mf-ERG were evaluated at baseline, 1 month, and 6 months throughout the follow-up period. The correlation of mf-ERG values and OCT features, BCVA, and the duration of disease were investigated. In the study group, the baseline P1 and N1 amplitudes were significantly lower than the control group, and P1 and N1 implicit times were significantly higher in patients with DME than in the control group in all rings (All p
ISSN:2459-1777
2587-0394
DOI:10.14744/bej.2021.60590