Description of a Cohort of Type 1 Diabetes Patients: Analysis of Comorbidities, Prevalence of Complications and Risk of Hypoglycemia

Despite major medical advances, Type 1 Diabetes (T1D) patients still have greater morbimortality than the general population. Our aim was to describe our cohort of T1D patients and identify potential risk factors susceptible to prevention strategies. Cross-sectional, observational study, including T...

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Published in:Journal of clinical medicine 2022-02, Vol.11 (4), p.1039
Main Authors: Martínez-Ortega, Antonio J, Muñoz-Gómez, Cristina, Gros-Herguido, Noelia, Remón-Ruiz, Pablo Jesús, Acosta-Delgado, Domingo, Losada-Viñau, Fernando, Pumar-López, Alfonso, Mangas-Cruz, Miguel Ángel, González-Navarro, Irene, López-Gallardo, Gema, Bellido, Virginia, Soto-Moreno, Alfonso Manuel
Format: Article
Language:English
Subjects:
Age
Cardiovascular disease
Clinical medicine
Comorbidity
Creatinine
Diabetes
Diabetic retinopathy
Disease prevention
Endocrinology
Hypertension
Hypoglycemia
Informed consent
Insulin
Kidney diseases
Males
Nutrition research
Patients
Risk factors
Variables
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Summary:Despite major medical advances, Type 1 Diabetes (T1D) patients still have greater morbimortality than the general population. Our aim was to describe our cohort of T1D patients and identify potential risk factors susceptible to prevention strategies. Cross-sectional, observational study, including T1D patients treated at our center, from 1 March 2017 to 31 March 2020. T1D, age > 14 years and signed informed consent. diabetes other than T1D, age < 14 years and/or refusal to participate. Study population = 2181 (49.8% females, median age at enrollment 41 years, median HbA1c 7.7%; 38.24% had at least one comorbidity). Roughly 7.45% had severe hypoglycemia (SH) within the prior year. Macro/microvascular complications were present in 42.09% (5.83% and 41.14%, respectively). The most frequent microvascular complication was diabetic retinopathy (38.02%), and coronary disease (3.21%) was the most frequent macrovascular complication. The risk of complications was higher in males than in females, mainly macrovascular. Patients with SH had a higher risk of complications (OR 1.42; 1.43 in males versus 1.42 in females). Our T1D population is similar to other T1D populations. We should minimize the risk of SH, and male patients should perhaps be treated more aggressively regarding cardiovascular risk factors.
ISSN:2077-0383
2077-0383
DOI:10.3390/jcm11041039