Effect of “Murcchana samskara” on therapeutic efficacy of BhallatakadiGhrita

‘Bhallatakadi Ghrita’ (BG), comprising the plant extracts of Semecarpus anacardium L., Argemone mexicana L., Cocculus hirsutus L., and Woodfordia fruticosa K. ‘Murcchana samskara’ of ghee before any ‘ghrita-paka’ preparation evidenced the maximum acceptability for topical application. The current st...

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Bibliographic Details
Published in:Journal of ayurveda and integrative medicine 2022-04, Vol.13 (2), p.100547-100547, Article 100547
Main Authors: Wayal, Sandesh R., Barke, Sonali A., Nigade, Ganesh, Jagtap, Pradnya, Gurav, Nilambari S., Prasad, Satyendra, Wanjari, Manish, Ayyanar, Muniappan, Gurav, Shailendra S.
Format: Article
Language:English
Subjects:
Aayurveda
Excision wound
Ghrita
Incision wound
Polyherbal
Short Communication
Wound breaking strength
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Summary:‘Bhallatakadi Ghrita’ (BG), comprising the plant extracts of Semecarpus anacardium L., Argemone mexicana L., Cocculus hirsutus L., and Woodfordia fruticosa K. ‘Murcchana samskara’ of ghee before any ‘ghrita-paka’ preparation evidenced the maximum acceptability for topical application. The current study dealt with the effect of the ‘Murcchana’ process on the therapeutic efficacy of BG. In the first step, ‘Murcchita’ ghee was prepared as per reference texts and then developed the ‘Murcchita Bhallatakadi Ghrita’ (M-BG), which was further assessed for wound healing activity using incision and excision wound animal models. ‘Murcchanasamskara’ altered the wound healing ability of M-BG (100% wound contraction on 15th post wounding day with 13.50 ± 0.22 days complete re-epithelization time and 562.33 ± 7.37 g breaking strength). The presence of antioxidants, polyphenols, flavonoids, and fatty acids (known for their potential wound healing properties) in M-BG could accelerate the wound contraction rate (P 
ISSN:0975-9476
0976-2809
DOI:10.1016/j.jaim.2022.100547