Early gastric cancer: A challenge in Western countries

Early gastric cancer (EGC) is an invasive carcinoma involving only the stomach mucosa or submucosa, independently of lymph node status. EGC represents over 50% of cases in Japan and in South Korea, whereas it accounts only for approximately 20% of all newly diagnosed gastric cancers in Western count...

Full description

Saved in:
Bibliographic Details
Published in:World journal of gastroenterology : WJG 2022-02, Vol.28 (7), p.693-703
Main Authors: Chiarello, Maria Michela, Fico, Valeria, Pepe, Gilda, Tropeano, Giuseppe, Adams, Neill James, Altieri, Gaia, Brisinda, Giuseppe
Format: Article
Language:English
Subjects:
Early Detection of Cancer
Gastric Mucosa - diagnostic imaging
Gastric Mucosa - pathology
Gastric Mucosa - surgery
Gastroscopy
Humans
Lymph Node Excision
Stomach Neoplasms - pathology
Stomach Neoplasms - surgery
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Early gastric cancer (EGC) is an invasive carcinoma involving only the stomach mucosa or submucosa, independently of lymph node status. EGC represents over 50% of cases in Japan and in South Korea, whereas it accounts only for approximately 20% of all newly diagnosed gastric cancers in Western countries. The main classification systems of EGC are the Vienna histopathologic classification and the Paris endoscopic classification of polypoid and non-polypoid lesions. A careful endoscopic assessment is fundamental to establish the best treatment of EGC. Generally, EGCs are curable if the lesion is completely removed by endoscopic resection or surgery. Some types of EGC can be resected endoscopically; for others the most appropriate treatment is surgical resection and D2 lymphadenectomy, especially in Western countries. The favorable oncological prognosis, the extended lymphadenectomy and the reconstruction of the intestinal continuity that excludes the duodenum make the prophylactic cholecystectomy mandatory to avoid the onset of biliary complications.
ISSN:1007-9327
2219-2840
DOI:10.3748/wjg.v28.i7.693