The Changes in Optic Nerve after Orbital Decompression Surgery for Thyroid Eye Disease and Case Reports of Ischemic Optic Neuropathy

Purpose. To demonstrate the changes in the retinal nerve fiber layer (RNFL) after orbital decompression for thyroid eye disease (TED). Methods. We retrospectively enrolled 52 surgical TED patients, 30 nonsurgical TED patients, and 30 control subjects. Five surgical TED eyes with disc edema were excl...

Full description

Saved in:
Bibliographic Details
Published in:BioMed research international 2022, Vol.2022, p.4808194-10
Main Authors: Hsia, Yun, Hsiao, Chia-Chieh, Wei, Yi-Hsuan, Lai, I-Wen, Lin, Chao-Wen, Liao, Shu-Lang
Format: Article
Language:English
Subjects:
Case reports
Decompression
Decompression - adverse effects
Edema
Eye
Eye diseases
Fibrosis
Generalized linear models
Graves Ophthalmopathy - surgery
Humans
Ischemia
Nerves
Occlusion
Optic nerve
Optic Nerve - diagnostic imaging
Optic Nerve - surgery
Optic Nerve Diseases - complications
Optic Nerve Diseases - surgery
Optic neuropathy
Optic Neuropathy, Ischemic - surgery
Optical Coherence Tomography
Patients
Retrospective Studies
Standard deviation
Surgery
Thickness
Thyroid
Thyroid gland
Tomography
Tomography, Optical Coherence - methods
Vision
Vision Disorders
Visual field
Visual fields
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Purpose. To demonstrate the changes in the retinal nerve fiber layer (RNFL) after orbital decompression for thyroid eye disease (TED). Methods. We retrospectively enrolled 52 surgical TED patients, 30 nonsurgical TED patients, and 30 control subjects. Five surgical TED eyes with disc edema were excluded. The surgical TED patients were classified into the “dysthyroid optic neuropathy (DON)” group (16 eyes) and the “non-DON” group (83 eyes). Optical coherence tomography (OCT) and visual field (VF) examinations were performed preoperatively and 6 months later. The control subjects and nonsurgical TED patients received two OCT examinations at 6-month intervals. The postoperative changes in the RNFL thickness were compared between groups. Three cases with severe postoperative vision loss were presented additionally. Results. The changes in the RNFL thickness of the controls (0.5±3.4 μm) and the nonsurgical TED patients (0.3±2.8 μm) were significantly smaller than the surgical TED patients (P
ISSN:2314-6133
2314-6141
DOI:10.1155/2022/4808194