The interaction of gut microbiota with parasitic protozoa

The human intestinal microbiota is composed of a complex combination of microorganisms including bacteria, virus, and eukaryotes. The microbiota plays a critical role in homeostasis through creating a mucosal barrier, providing protective responses to pathogens, and affecting the immune system and m...

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Bibliographic Details
Published in:Journal of parasitic diseases 2022-03, Vol.46 (1), p.8-11
Main Authors: Ulusan Bagci, Ozlem, Caner, Ayse
Format: Article
Language:English
Subjects:
Health Promotion and Disease Prevention
Homeostasis
Immune response
Infectious Diseases
Infectivity
Intestinal microflora
Medicine
Medicine & Public Health
Microbiota
Mucosa
Physiology
Protozoa
Short Communication
Virulence
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Summary:The human intestinal microbiota is composed of a complex combination of microorganisms including bacteria, virus, and eukaryotes. The microbiota plays a critical role in homeostasis through creating a mucosal barrier, providing protective responses to pathogens, and affecting the immune system and metabolism of the host. Molecules secreted by parasites can alter composition of microbiota both by acting directly on the microbial community and indirectly by affecting the host physiology . On the other hand, the microbiota composition can affect the survival, physiology, and virulence of many parasitic protozoa. Explanation of possible interactions between the microbiota, immune response, and protozoa may further clarify the underlying mechanisms of infectivity, clinical variations, and life-cycle of protozoa.
ISSN:0971-7196
0975-0703
DOI:10.1007/s12639-021-01443-5