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Left Hemiplegia Possibly Due to Glucose Reperfusion Injury after Recovery of Severe Hypoglycemia in a Woman with Type 2 Diabetes Mellitus
A 79-year-old woman with type 2 diabetes receiving insulin was rushed to our hospital due to severe hypoglycemia. Glucose was administered, and the consciousness disturbance was promptly improved. A few hours later, conjugate deviation of the eyes to the right and left hemiplegia occurred at a norma...
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Published in: | Internal Medicine 2022/02/15, Vol.61(4), pp.513-516 |
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container_title | Internal Medicine |
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creator | Sugito, Erika Tsujimoto, Tetsuro Arai, Noritoshi Bouchi, Ryotaro Ohsugi, Mitsuru Tanabe, Akiyo Ueki, Kohjiro Kajio, Hiroshi |
description | A 79-year-old woman with type 2 diabetes receiving insulin was rushed to our hospital due to severe hypoglycemia. Glucose was administered, and the consciousness disturbance was promptly improved. A few hours later, conjugate deviation of the eyes to the right and left hemiplegia occurred at a normal glucose level. Cerebral magnetic resonance imaging (MRI) showed hyperintensities of the right posterior limb of the internal capsule and the medial thalamus on diffusion-weighted imaging sequences. However, the changes observed using MRI disappeared completely on the third day, and her symptoms subsequently improved. This may have been a case of glucose reperfusion injury. |
doi_str_mv | 10.2169/internalmedicine.7202-21 |
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Glucose was administered, and the consciousness disturbance was promptly improved. A few hours later, conjugate deviation of the eyes to the right and left hemiplegia occurred at a normal glucose level. Cerebral magnetic resonance imaging (MRI) showed hyperintensities of the right posterior limb of the internal capsule and the medial thalamus on diffusion-weighted imaging sequences. However, the changes observed using MRI disappeared completely on the third day, and her symptoms subsequently improved. This may have been a case of glucose reperfusion injury.</description><identifier>ISSN: 0918-2918</identifier><identifier>EISSN: 1349-7235</identifier><identifier>DOI: 10.2169/internalmedicine.7202-21</identifier><identifier>PMID: 34393160</identifier><language>eng</language><publisher>Japan: The Japanese Society of Internal Medicine</publisher><subject>Aged ; Case Report ; Diabetes ; Diabetes mellitus (non-insulin dependent) ; Diabetes Mellitus, Type 2 - complications ; Female ; Glucose ; glucose reperfusion ; Hemiplegia ; Hemiplegia - etiology ; Humans ; Hypoglycemia ; Hypoglycemia - etiology ; hypoglycemic encephalopathy ; Insulin ; Internal medicine ; Magnetic resonance imaging ; Magnetic Resonance Imaging - methods ; neuronal damage ; Reperfusion ; Reperfusion Injury ; Thalamus</subject><ispartof>Internal Medicine, 2022/02/15, Vol.61(4), pp.513-516</ispartof><rights>2022 by The Japanese Society of Internal Medicine</rights><rights>Copyright Japan Science and Technology Agency 2022</rights><rights>Copyright © 2022 by The Japanese Society of Internal Medicine</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c609t-7462cabd3185b433100921bc1afc3b716e755c38ff209c45bcb78c508721b78d3</citedby><cites>FETCH-LOGICAL-c609t-7462cabd3185b433100921bc1afc3b716e755c38ff209c45bcb78c508721b78d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907763/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907763/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27923,27924,53790,53792</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34393160$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sugito, Erika</creatorcontrib><creatorcontrib>Tsujimoto, Tetsuro</creatorcontrib><creatorcontrib>Arai, Noritoshi</creatorcontrib><creatorcontrib>Bouchi, Ryotaro</creatorcontrib><creatorcontrib>Ohsugi, Mitsuru</creatorcontrib><creatorcontrib>Tanabe, Akiyo</creatorcontrib><creatorcontrib>Ueki, Kohjiro</creatorcontrib><creatorcontrib>Kajio, Hiroshi</creatorcontrib><title>Left Hemiplegia Possibly Due to Glucose Reperfusion Injury after Recovery of Severe Hypoglycemia in a Woman with Type 2 Diabetes Mellitus</title><title>Internal Medicine</title><addtitle>Intern. Med.</addtitle><description>A 79-year-old woman with type 2 diabetes receiving insulin was rushed to our hospital due to severe hypoglycemia. Glucose was administered, and the consciousness disturbance was promptly improved. A few hours later, conjugate deviation of the eyes to the right and left hemiplegia occurred at a normal glucose level. Cerebral magnetic resonance imaging (MRI) showed hyperintensities of the right posterior limb of the internal capsule and the medial thalamus on diffusion-weighted imaging sequences. However, the changes observed using MRI disappeared completely on the third day, and her symptoms subsequently improved. This may have been a case of glucose reperfusion injury.</description><subject>Aged</subject><subject>Case Report</subject><subject>Diabetes</subject><subject>Diabetes mellitus (non-insulin dependent)</subject><subject>Diabetes Mellitus, Type 2 - complications</subject><subject>Female</subject><subject>Glucose</subject><subject>glucose reperfusion</subject><subject>Hemiplegia</subject><subject>Hemiplegia - etiology</subject><subject>Humans</subject><subject>Hypoglycemia</subject><subject>Hypoglycemia - etiology</subject><subject>hypoglycemic encephalopathy</subject><subject>Insulin</subject><subject>Internal medicine</subject><subject>Magnetic resonance imaging</subject><subject>Magnetic Resonance Imaging - methods</subject><subject>neuronal damage</subject><subject>Reperfusion</subject><subject>Reperfusion Injury</subject><subject>Thalamus</subject><issn>0918-2918</issn><issn>1349-7235</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNplkdtu1DAQhi0EokvhFZAlbrhJ8SGJnRsk1EK30nIQFHFpOd7JrleJndpOUR6Bt8arXVZQbsa25pvfM_MjhCm5YLRu3liXIDjdD7C2xjq4EIywgtFHaEF52RSC8eoxWpCGyoLlcIaexbgjhEvRsKfojJe84bQmC_RrBV3CSxjs2MPGavzFx2jbfsZXE-Dk8XU_GR8Bf4URQjdF6x2-cbspzFh3uYucMP4e8tN3-BvkG-DlPPpNP5usqrF1WOMfftAO_7Rpi2_nETDDV1a3kCDij9D3Nk3xOXrS6T7Ci-N5jr5_eH97uSxWn69vLt-tClOTJhWirJnR7ZpTWbUl55SQhtHWUN0Z3gpag6gqw2XXMdKYsmpNK6SpiBSZEnLNz9Hbg-44tXl_BlwKuldjsIMOs_Laqn8zzm7Vxt8r2RAhap4FXh8Fgr-bICY12GjyFNqBn6JiVU0bxutSZvTVA3Tnp71xmap5KWUpWJkpeaBMyMsP0J2aoUTt_VYP_VZ7v3Mql778e5hT4R-DM_DpAOxi0hs4AToka3r4X7mmqtyH4w8n0Gx1UOD4b7Nxyus</recordid><startdate>20220215</startdate><enddate>20220215</enddate><creator>Sugito, Erika</creator><creator>Tsujimoto, Tetsuro</creator><creator>Arai, Noritoshi</creator><creator>Bouchi, Ryotaro</creator><creator>Ohsugi, Mitsuru</creator><creator>Tanabe, Akiyo</creator><creator>Ueki, Kohjiro</creator><creator>Kajio, Hiroshi</creator><general>The Japanese Society of Internal Medicine</general><general>Japan Science and Technology Agency</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7TK</scope><scope>7U9</scope><scope>H94</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20220215</creationdate><title>Left Hemiplegia Possibly Due to Glucose Reperfusion Injury after Recovery of Severe Hypoglycemia in a Woman with Type 2 Diabetes Mellitus</title><author>Sugito, Erika ; 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subjects | Aged Case Report Diabetes Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 - complications Female Glucose glucose reperfusion Hemiplegia Hemiplegia - etiology Humans Hypoglycemia Hypoglycemia - etiology hypoglycemic encephalopathy Insulin Internal medicine Magnetic resonance imaging Magnetic Resonance Imaging - methods neuronal damage Reperfusion Reperfusion Injury Thalamus |
title | Left Hemiplegia Possibly Due to Glucose Reperfusion Injury after Recovery of Severe Hypoglycemia in a Woman with Type 2 Diabetes Mellitus |
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