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Comparison of numerical and standard sarnat grading using the NICHD and SIBEN methods

Objective The NICHD and SIBEN assessments are adapted from the Sarnat grade, and used to determine severity of neonatal encephalopathy (NE). We compare NICHD and SIBEN methods, and their ability to define a minimum threshold associated with significant cerebral injury. Study design Between 2016 and...

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Bibliographic Details
Published in:Journal of perinatology 2022-03, Vol.42 (3), p.328-334
Main Authors: Walsh, Brian H., Munster, Chelsea, El-Shibiny, Hoda, Yang, Edward, Inder, Terrie E., El-Dib, Mohamed
Format: Article
Language:English
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Summary:Objective The NICHD and SIBEN assessments are adapted from the Sarnat grade, and used to determine severity of neonatal encephalopathy (NE). We compare NICHD and SIBEN methods, and their ability to define a minimum threshold associated with significant cerebral injury. Study design Between 2016 and 2019, 145 infants with NE (77-mild; 65-moderate; 3-severe) were included. NICHD and SIBEN grade and numerical scores were assigned. Kappa scores described agreement between methods, and ROC curves their ability to predict MR injury. Results Good agreement existed between grading systems ( K  = 0.86). SIBEN defined more infants as moderate, and less as mild, than NICHD ( p  
ISSN:0743-8346
1476-5543
DOI:10.1038/s41372-021-01180-w