The prognostic values of thyroid disorders in predicting COVID-19 composite poor outcomes: A systematic review and meta-analysis

In this meta-analysis, we aimed to evaluate the prognostic properties of thyroid disorder during admission on poor prognosis and factors that may influence the relationship in patients with COVID-19. A systematic literature search of PubMed, EBSCO, and CENTRAL was conducted from inception to August...

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Bibliographic Details
Published in:Diabetes & metabolic syndrome clinical research & reviews 2022-05, Vol.16 (5), p.102464-102464, Article 102464
Main Authors: Permana, Hikmat, Soeriadi, Erwin Affandi, Damara, Fachreza Aryo, Mulyani Soetedjo, Nanny Natalia
Format: Article
Language:English
Subjects:
COVID-19
COVID-19 - diagnosis
COVID-19 - epidemiology
Humans
Hypothyroidism
Prognosis
Reviews and Meta-analysis
SARS-CoV-2
Thyroid Diseases - complications
Thyroid Diseases - diagnosis
Thyroid Diseases - epidemiology
Thyroid disorder
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Summary:In this meta-analysis, we aimed to evaluate the prognostic properties of thyroid disorder during admission on poor prognosis and factors that may influence the relationship in patients with COVID-19. A systematic literature search of PubMed, EBSCO, and CENTRAL was conducted from inception to August 27, 2021. The main exposure was unspecified and specified thyroid disorders–hypothyroidism or hypothyroidism. The outcome of interest was the COVID-19 composite poor outcome that comprises of severity, mortality, ICU admission, and hospitalization. There were 24,734 patients from 20 studies. Meta-analysis showed that thyroid disorder was associated with composite poor outcome (OR 2.87 (95% CI 2.04–4.04), p 
ISSN:1871-4021
1878-0334
DOI:10.1016/j.dsx.2022.102464