Nomograms for Predicting the Risk of SIRS and Urosepsis after Uroscopic Minimally Invasive Lithotripsy

Objective. To analyze the potential risk factors that affect the development of urosepsis following uroscopic minimally invasive lithotripsy and to develop a nomogram that predicts the probability of postoperative urosepsis. Methods. We retrospectively analyzed the clinical data from patients that u...

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Bibliographic Details
Published in:BioMed research international 2022-03, Vol.2022, p.6808239-8
Main Authors: Wang, Can, Xu, Rufu, Zhang, Yuanning, Wu, Yingbing, Zhang, Teng, Dong, Xingyou, Zhang, Rong, Hu, Xuelian
Format: Article
Language:English
Subjects:
Biomarkers
Blood
C-Reactive Protein
Complications and side effects
Failure analysis
Gender
Health aspects
Humans
Infections
Inflammation
Inflammatory response
Kidney Calculi - surgery
Laboratories
Leukocytes (neutrophilic)
Lithotripsy
Lithotripsy - adverse effects
Multivariate analysis
Nephrolithotomy, Percutaneous - adverse effects
Nomograms
Nomography (Mathematics)
Patients
Postoperative Complications - diagnosis
Postoperative Complications - etiology
Procalcitonin
Regression analysis
Retrospective Studies
Risk analysis
Risk Factors
Sepsis
Sepsis - diagnosis
Sepsis - etiology
Statistical analysis
Surgery
Systemic inflammatory response syndrome
Systemic Inflammatory Response Syndrome - diagnosis
Systemic Inflammatory Response Syndrome - etiology
Urinary tract diseases
Urinary Tract Infections - complications
Urine
Urogenital system
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Summary:Objective. To analyze the potential risk factors that affect the development of urosepsis following uroscopic minimally invasive lithotripsy and to develop a nomogram that predicts the probability of postoperative urosepsis. Methods. We retrospectively analyzed the clinical data from patients that underwent percutaneous nephrolithotripsy (PCNL) or ureteroscopic lithotripsy (URL) between January 2018 and December 2019. The enrolled patients were grouped twice according to systemic inflammatory response syndrome (SIRS) and quick sequential organ failure assessment (qSOFA). After univariate and multivariate logistic regression analyses, we identified the independent predictive factors affecting the development of postoperative SIRS and urosepsis, and built the nomograms. Results. From January 2018 to December 2019, 1959 patients underwent PCNL or URL, of whom 236 patients were accorded with the inclusion criteria. Of all 236 patients, 64 (27.12%) patients developed postoperative SIRS, and 17 (7.20%) patients developed postoperative urosepsis. Multivariate logistic regression analysis showed that positive preoperative urine culture (PUC+) (OR=2.331, P=0.044), procalcitonin (PCT) (OR=1.093, P=0.037), C-reactive protein (CRP) (OR=1.017, P
ISSN:2314-6133
2314-6141
DOI:10.1155/2022/6808239