Roles of Microbiota in Cancer: From Tumor Development to Treatment

Cancer as a second leading cause of death arises from multifactorial pathology. The association of microbiota and their products with various pathologic conditions including cancer is receiving significant attention over the past few years. Mounting evidence showed that human microbiota is an emergi...

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Bibliographic Details
Published in:Journal of oncology 2022-03, Vol.2022, p.3845104-15
Main Authors: Bagheri, Zohreh, Moeinzadeh, Leila, Razmkhah, Mahboobeh
Format: Article
Language:English
Subjects:
Animals
Bacteria
Cancer
Cancer therapies
Development and progression
Diet
Dietary fiber
Drug therapy
Health aspects
Homeostasis
Immune system
Inflammation
Metabolism
Metabolites
Metronidazole
Microbiota
Microbiota (Symbiotic organisms)
Microorganisms
Permeability
Physiology
Review
Tumors
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Summary:Cancer as a second leading cause of death arises from multifactorial pathology. The association of microbiota and their products with various pathologic conditions including cancer is receiving significant attention over the past few years. Mounting evidence showed that human microbiota is an emerging target in tumor onset, progression, prevention, and even diagnosis. Accordingly, modulating this composition might influence the response to tumor therapy and therapeutic resistance as well. Through this review, one could conceive of complex interaction between the microbiome and cancer in either positive or negative manner by which may hold potential for finding novel preventive and therapeutic strategies against cancer.
ISSN:1687-8450
1687-8450
DOI:10.1155/2022/3845104