Hematological Changes in the Second Wave of SARS-CoV-2 in North India

Background COVID-19 is a rapidly spreading pandemic caused by SARS-CoV-2. India experienced a second wave peak in mid of April 2021, and it emerged as a medical crisis. This study was taken up to show if the hematological and peripheral blood changes can be used as a readily available tool to demarc...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2022-03, Vol.14 (3), p.e23495-e23495
Main Authors: Singh, Akanksha, Verma, Shailendra P, Kushwaha, Rashmi, Ali, Wahid, Reddy, Himanshu D, Singh, Uma S
Format: Article
Language:English
Subjects:
Blood platelets
Blood tests
Coronaviruses
COVID-19
Disease transmission
Hematology
Hemoglobin
Infections
Infectious Disease
Intensive care
Lymphocytes
Morphology
Neutrophils
Pathology
Severe acute respiratory syndrome coronavirus 2
Thrombocytopenia
Viral infections
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Summary:Background COVID-19 is a rapidly spreading pandemic caused by SARS-CoV-2. India experienced a second wave peak in mid of April 2021, and it emerged as a medical crisis. This study was taken up to show if the hematological and peripheral blood changes can be used as a readily available tool to demarcate the patients needing ICU care so that the ICU can be utilized more prudently.  Material and method One hundred reverse transcription-polymerase chain reaction (RT-PCR) confirmed cases of COVID-19, 50 each from ICU and non-ICU wards, were included in this observational study. At the time of admission blood sample was collected for evaluation of hematological parameters. Results We noted that 74% of patients admitted in ICU were males and 28% were more than 60 years of age. In ICU patients, the absolute neutrophil count (ANC) was significantly raised when compared to non-ICU cases (p=0.023). The nadir absolute lymphocyte count (ALC) was 0.11x10 /L in ICU patients and 0.95x10 /L in non-ICU patients. There was a significant increase in neutrophil-lymphocyte ratio (NLR; p
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.23495