Management of Diagnosis and Treatment in a Case of Fibrolamellar Carcinoma

Fibrolamellar carcinoma is a rare primary hepatic malignancy that has recently been recognized as a distinct clinical entity, highly different from the well-known hepatocellular carcinoma. This report describes the clinical and paraclinical aspects of the fibrolamellar carcinoma, emphasizing its par...

Full description

Saved in:
Bibliographic Details
Published in:Cancer diagnosis & prognosis 2021-03, Vol.1 (1), p.23-28
Main Authors: Bacinschi, Xenia, Zgura, Anca Florina, Mercan-Stanciu, Adriana, Grasu, Mugur, Herlea, Vlad, Toma, Letitia, Dodot, Mihai, Martiniuc, Alexandru, Anghel, Rodica, Haineala, Bogdan
Format: Article
Language:English
Subjects:
Case Report
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Fibrolamellar carcinoma is a rare primary hepatic malignancy that has recently been recognized as a distinct clinical entity, highly different from the well-known hepatocellular carcinoma. This report describes the clinical and paraclinical aspects of the fibrolamellar carcinoma, emphasizing its particularities. A 30-year-old patient presented to the hospital with nonspecific symptoms and weight loss, with imaging findings showing abdominal and mediastinal masses. Multiple biopsies were performed, leading to a diagnosis of metastatic fibrolamellar carcinoma. Given the extent of the disease, systemic drug treatment was administered, although prognosis was poor with tumor growth, resulting in biliary duct invasion. Fibrolamellar carcinoma is a rare type of malignancy, with a difficult differential diagnosis in which imaging techniques are important but for which biopsy remains the gold standard. The prognosis depends on tumor extent and may include surgical methods or chemotherapy.
ISSN:2732-7787
2732-7787
DOI:10.21873/cdp.10004