Older patients with eosinophilic esophagitis have high treatment response to topical steroids

There are few data assessing treatment response in older eosinophilic esophagitis (EoE) patients and we evaluated treatment outcomes to topical corticosteroids (tCS) in this older population. This retrospective cohort study of the UNC EoE Clinicopathologic database included subjects with a new diagn...

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Bibliographic Details
Published in:Digestive and liver disease 2022-04, Vol.54 (4), p.477-482
Main Authors: Ketchem, Corey J., Thakkar, Kisan P., Xue, Angela, Reddy, Sumana, Abramson, Lior, Greenberg, Sydney B., Abichandani, Sonia, Miller, Talya L., Chang, Nicole C., Eluri, Swathi, Reed, Craig C., Dellon, Evan S.
Format: Article
Language:English
Subjects:
Aged
Eosinophilic esophagitis
Eosinophilic Esophagitis - diagnosis
Eosinophils
Glucocorticoids - therapeutic use
Humans
Older age
Retrospective Studies
Steroids - therapeutic use
Topical steroids
Treatment outcomes
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Summary:There are few data assessing treatment response in older eosinophilic esophagitis (EoE) patients and we evaluated treatment outcomes to topical corticosteroids (tCS) in this older population. This retrospective cohort study of the UNC EoE Clinicopathologic database included subjects with a new diagnosis of EoE treated with tCS. Histologic responses, global symptom response, and endoscopic changes were recorded. Older EoE patients (≥65 years) were compared to younger EoE patients (
ISSN:1590-8658
1878-3562
DOI:10.1016/j.dld.2021.10.004