Regulation of heat shock proteins 70 and their role in plant immunity

• Published in: Journal of experimental botany 2022-04, Vol.73 (7), p.1894-1909
• Main Authors: Berka, Miroslav, Kopecká, Romana, Berková, Veronika, Brzobohatý, Břetislav, Černý, Martin
• Format: Article
• Language: English
• Subjects: Animals; HSP70 Heat-Shock Proteins - metabolism; Mammals - metabolism; Plant Immunity; Review Papers; Signal Transduction
• ISSN: 0022-0957; 1460-2431
• DOI: 10.1093/jxb/erab549

The extensive regulation of HSP70 has received little attention in plant science. Here, we summarize current knowledge gained in large-scale profiling experiments and highlight HSP70s’ role in plant immunity. Abstract Heat shock proteins 70 (HSP70s) are steadily gaining more attention in the field of plant biotic interactions. Though their regulation and activity in plants are much less well characterized than are those of their counterparts in mammals, accumulating evidence indicates that the role of HSP70-mediated defense mechanisms in plant cells is indispensable. In this review, we summarize current knowledge of HSP70 post-translational control in plants. We comment on the phytohormonal regulation of HSP70 expression and protein abundance, and identify a prominent role for cytokinin in HSP70 control. We outline HSP70s’ subcellular localizations, chaperone activity, and chaperone-mediated protein degradation. We focus on the role of HSP70s in plant pathogen-associated molecular pattern-triggered immunity and effector-triggered immunity, and discuss the contribution of different HSP70 subfamilies to plant defense against pathogens.