Blood purification for sepsis: an overview

Abstract Sepsis is a life-threatening organ failure exacerbated by a maladaptive infection response from the host, and is one of the major causes of mortality in the intensive care unit. In recent decades, several extracorporeal blood purification techniques have been developed to manage sepsis by a...

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Bibliographic Details
Published in:Precision clinical medicine 2021-03, Vol.4 (1), p.45-55
Main Authors: Zhang, Ling, Feng, Yuying, Fu, Ping
Format: Article
Language:English
Subjects:
Review
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Summary:Abstract Sepsis is a life-threatening organ failure exacerbated by a maladaptive infection response from the host, and is one of the major causes of mortality in the intensive care unit. In recent decades, several extracorporeal blood purification techniques have been developed to manage sepsis by acting on both the infectious agents themselves and the host immune response. This research aims to summarize recent progress on extracorporeal blood purification technologies applied for sepsis, discuss unanswered questions on renal replacement therapy for septic patients, and present a decision-making strategy for practitioners.
ISSN:2096-5303
2516-1571
DOI:10.1093/pcmedi/pbab005