A Rare Case of Purpura Fulminans in the Setting of Klebsiella pneumoniae Bacteremia

A 23-year-old man with circulatory shock associated with severe sepsis and congestive heart failure with an ejection fraction of 10% resulting in anasarca and multiorgan failure was admitted to our hospital's intensive care unit. Hours after admission, he developed a rash on his left inner thig...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2022-03, Vol.14 (3), p.e22921
Main Authors: Ruiz de Villa, Ariel, Charles, Kipson, Okonoboh, Peters
Format: Article
Language:English
Subjects:
Abdomen
Blood
Case reports
Chicken pox
Edema
Etiology
Gangrene
Heart failure
Hematology
Infectious Disease
Internal Medicine
Laboratories
Mortality
Patients
Pleural effusion
Pneumonia
Proteins
Purpura
Streptococcus infections
Thrombosis
Ultrasonic imaging
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Summary:A 23-year-old man with circulatory shock associated with severe sepsis and congestive heart failure with an ejection fraction of 10% resulting in anasarca and multiorgan failure was admitted to our hospital's intensive care unit. Hours after admission, he developed a rash on his left inner thigh, which was later diagnosed as purpura fulminans (PF). Blood cultures were consistent with bacteremia, with community-acquired pneumonia being the possible source. PF is a rare and difficult-to-diagnose entity characterized by dysregulated hemostasis that is often associated with poor prognosis and fatal outcomes. To our knowledge, there are limited reports in the literature on . as a cause of PF. Given the rarity of this presentation, this case will serve as an opportunity to report and discuss the pathophysiology of this disease for the benefit of physicians.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.22921