Frailty is a predictor of moderate to severe pain after robot‐assisted laparoscopic prostatectomy: A case‐control study (FRAP study)

• Published in: BJUI compass 2020-07, Vol.1 (3), p.100-107
• Main Authors: Momota, Masaki, Hatakeyama, Shingo, Soma, Osamu, Hamano, Itsuto, Fujita, Naoki, Okamoto, Teppei, Togashi, Kyo, Hamaya, Tomoko, Yoneyama, Tohru, Yamamoto, Hayato, Yoneyama, Takahiro, Hashimoto, Yasuhiro, Ohyama, Chikara
• Format: Article
• Language: English
• Subjects: Activities of daily living; Analgesics; Cardiovascular disease; Diabetes; Dissection; Fentanyl; Frailty; geriatric 8; Geriatrics; Hypertension; Laparoscopy; Lymphatic system; Morphine; Nonsteroidal anti-inflammatory drugs; Original; Pain; Patients; Prostate cancer; prostatectomy; Respiratory diseases; Statistical analysis; Surgeons
• ISSN: 2688-4526; 2688-4526
• DOI: 10.1002/bco2.17

Objective To investigate the association of pain with frailty in patients with localized prostate cancer (PC) who underwent robot‐assisted laparoscopic radical prostatectomy (RARP). Materials and Methods Between January 2017 and June 2019, we prospectively evaluated the geriatric 8 (G8) score, simplified frailty index (sFI), and numerical rating scale (NRS) of 154 patients with localized PC who underwent RARP at our institution. NRS was measured on preoperative day 0, postoperative days 1, 2, 3, and at discharge. Moderate to severe pain was defined as NRS ≥ 5, whereas frailty was defined as G8 ≤ 14. The primary objectives of this study were to investigate the effects of moderate to severe pain (NRS ≥ 5) on frailty, postoperative complications, and the use of analgesics after RARP. Our secondary objectives were the effect of frailty on postoperative complications and the use of analgesics. Results The median age of participants was 69 years. Of 154 patients, 37 (24%) and 61 (40%) were classified to have NRS ≥ 5 and G8 ≤ 14, respectively. Patients with NRS > 5 presented significantly association with G8