Drug-Related Problems and Polypharmacy in Nursing Home Residents: A Cross-Sectional Study

At present, 19.2% of the Spanish population is aged 65 or older. Polypharmacy is a frequent condition among the elderly, especially in those living in nursing homes, which is associated with adverse outcomes, such as adverse drug events or drug-drug interactions. This study aimed to assess the patte...

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Published in:International journal of environmental research and public health 2022-04, Vol.19 (7), p.4313
Main Authors: Díez, Raquel, Cadenas, Raquel, Susperregui, Julen, Sahagún, Ana M, Fernández, Nélida, García, Juan J, Sierra, Matilde, López, Cristina
Format: Article
Language:English
Subjects:
Aged
Aging
Anticholinergics
Benzodiazepines
Chronic illnesses
Cross-Sectional Studies
Drug development
Drug Interactions
Drug-Related Side Effects and Adverse Reactions - epidemiology
Evaluation
Geriatrics
Humans
Inappropriate Prescribing
Institutionalization
Nervous system
Nursing Homes
Older people
Polypharmacy
Population
Risk
Software
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cited_by cdi_FETCH-LOGICAL-c418t-2717a5fc43866abea902c2b539d7aff0fbe3d06718188212b23dd9b5d853c4063
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container_title International journal of environmental research and public health
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creator Díez, Raquel
Cadenas, Raquel
Susperregui, Julen
Sahagún, Ana M
Fernández, Nélida
García, Juan J
Sierra, Matilde
López, Cristina
description At present, 19.2% of the Spanish population is aged 65 or older. Polypharmacy is a frequent condition among the elderly, especially in those living in nursing homes, which is associated with adverse outcomes, such as adverse drug events or drug-drug interactions. This study aimed to assess the pattern of polypharmacy in a nursing home in Leon, one of Spain's most ageing regions, and its relationship with different drug-related problems. A descriptive, observational, and cross-sectional study design was used; 222 residents were involved in this study. Data on drug use were collected from medical charts. Information was screened with the software CheckTheMeds, BOT PLUS and Drug-Reax. Residents were on a median of 7 medicines. Polypharmacy and inappropriate medications were present in 78.8% and 96.8% of residents, respectively. Drug-related problems were present in almost all the populations evaluated. Drug-drug interactions were very common in participants (81.1%), being severe/moderate in 24.7%. A high prevalence of polypharmacy and drug-related problems in the nursing home population assessed has been observed. A significantly higher risk of suffering drug-drug interactions was revealed for increasing polypharmacy and anticholinergic risk. A regular evaluation of drug prescribing in nursing home residents is necessary to minimize drug-related problems risk.
doi_str_mv 10.3390/ijerph19074313
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subjects Aged
Aging
Anticholinergics
Benzodiazepines
Chronic illnesses
Cross-Sectional Studies
Drug development
Drug Interactions
Drug-Related Side Effects and Adverse Reactions - epidemiology
Evaluation
Geriatrics
Humans
Inappropriate Prescribing
Institutionalization
Nervous system
Nursing Homes
Older people
Polypharmacy
Population
Risk
Software
title Drug-Related Problems and Polypharmacy in Nursing Home Residents: A Cross-Sectional Study
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