Melissa officinalis : Composition, Pharmacological Effects and Derived Release Systems-A Review

is a medicinal plant rich in biologically active compounds which is used worldwide for its therapeutic effects. Chemical studies on its composition have shown that it contains mainly flavonoids, terpenoids, phenolic acids, tannins, and essential oil. The main active constituents of are volatile comp...

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Bibliographic Details
Published in:International journal of molecular sciences 2022-03, Vol.23 (7), p.3591
Main Authors: Petrisor, Gabriela, Motelica, Ludmila, Craciun, Luminita Narcisa, Oprea, Ovidiu Cristian, Ficai, Denisa, Ficai, Anton
Format: Article
Language:English
Subjects:
Acids
Antimicrobial agents
Bioactive compounds
Biological activity
Caffeic acid
Chemical composition
Chemical compounds
Chlorogenic acid
Citronellal
Composition effects
Controlled release
Delayed-Action Preparations
Essential oils
Flavonoids
Flavonoids - pharmacology
Geranial
Herbal medicine
Medical research
Melissa - chemistry
Melissa officinalis
Neral
Oils & fats
Oils, Volatile - chemistry
Oils, Volatile - pharmacology
Oleanolic acid
Pharmaceuticals
Pharmacology
Phenolic acids
Phytochemicals
Plant Extracts - chemistry
Plants, Medicinal
Quercetin
Review
Rosmarinic acid
Triterpenes
Ursolic acid
Volatile compounds
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Description
Summary:is a medicinal plant rich in biologically active compounds which is used worldwide for its therapeutic effects. Chemical studies on its composition have shown that it contains mainly flavonoids, terpenoids, phenolic acids, tannins, and essential oil. The main active constituents of are volatile compounds (geranial, neral, citronellal and geraniol), triterpenes (ursolic acid and oleanolic acid), phenolic acids (rosmarinic acid, caffeic acid and chlorogenic acid), and flavonoids (quercetin, rhamnocitrin, and luteolin). According to the biological studies, the essential oil and extracts of have active compounds that determine many pharmacological effects with potential medical uses. A new field of research has led to the development of controlled release systems with active substances from plants. Therefore, the essential oil or extract of has become a major target to be incorporated into various controlled release systems which allow a sustained delivery.
ISSN:1422-0067
1661-6596
1422-0067
DOI:10.3390/ijms23073591