Clinical characteristics and hematological parameters associated with disease severity in COVID‐19 positive pregnant women undergoing cesarean section: A single‐center experience

Aim The study aimed to describe clinical characteristics and outcomes of pregnant women with COVID‐19 undergoing cesarean section, and evaluated the association of blood values at admission with severe COVID‐19 disease in this group of patients. Method We retrospectively analyzed the clinical data o...

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Bibliographic Details
Published in:Journal of Obstetrics and Gynaecology Research 2022-02, Vol.48 (2), p.402-410
Main Authors: Arslan, Baris, Bicer, Ilhan G., Sahin, Tuna, Vay, Merve, Dilek, Okan, Destegul, Emre
Format: Article
Language:English
Subjects:
Alanine
Alanine transaminase
Aspartate transaminase
Blood groups
Cesarean Section
COVID-19
Female
Ferritin
Humans
L-Lactate dehydrogenase
Lactic acid
Leukocytes (neutrophilic)
Lymphocytes
maternal outcome
Original
Patients
Pregnancy
Pregnant Women
Procalcitonin
Retrospective Studies
ROC Curve
SARS-CoV-2
Severity of Illness Index
Transaminase
Turkey
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Summary:Aim The study aimed to describe clinical characteristics and outcomes of pregnant women with COVID‐19 undergoing cesarean section, and evaluated the association of blood values at admission with severe COVID‐19 disease in this group of patients. Method We retrospectively analyzed the clinical data of 110 patients infected with COVID‐19 who underwent cesarean section at Adana City Education and Research Hospital in Turkey. The COVID‐19 severity of the patients was classified as either severe or nonsevere disease according to World Health Organization of COVID‐19 clinical management guidance. We compared blood values, clinical characteristics, and outcomes between severe and nonsevere patients. Receiver operating characteristics (ROC) curves analyses and area under the ROC curve (AUC) value was calculated to evaluate the predictive value of blood parameters on the COVID‐19 severity. Results Of the 110 women, 12 were severe cases. Severe patients had higher ferritin, neutrophil‐to‐lymphocyte ratio (NLR), lactate dehydrogenase (LDH), alanine transaminase (ALT), aspartate transaminase (AST), and procalcitonin levels on admission (p
ISSN:1341-8076
1447-0756
DOI:10.1111/jog.15108