Genome-Wide Analysis of the LRR-RLP Gene Family in a Wild Banana ( Musa acuminata ssp. malaccensis ) Uncovers Multiple Fusarium Wilt Resistance Gene Candidates

Banana is the most popular fruit in the world, with a relevant role in food security for more than 400 million people. However, fungal diseases cause substantial losses every year. A better understanding of the banana immune system should facilitate the development of new disease-resistant cultivars...

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Bibliographic Details
Published in:Genes 2022-04, Vol.13 (4), p.638
Main Authors: Álvarez-López, Dulce, Herrera-Valencia, Virginia Aurora, Góngora-Castillo, Elsa, García-Laynes, Sergio, Puch-Hau, Carlos, López-Ochoa, Luisa Alhucema, Lizama-Uc, Gabriel, Peraza-Echeverria, Santy
Format: Article
Language:English
Subjects:
Bananas
Binding sites
Chromosome 10
Cultivars
Disease resistance
Disease Resistance - genetics
Food security
Fusarium
Fusarium - genetics
Genes
Genomes
Humans
Immune system
Kinases
Localization
Musa - genetics
Musa acuminata
Pathogens
Phylogeny
Plant diseases
Plant Diseases - genetics
Plant Diseases - microbiology
Proteins
Transcriptome
Transcriptomics
Wilt
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Summary:Banana is the most popular fruit in the world, with a relevant role in food security for more than 400 million people. However, fungal diseases cause substantial losses every year. A better understanding of the banana immune system should facilitate the development of new disease-resistant cultivars. In this study, we performed a genome-wide analysis of the leucine-rich repeat receptor-like protein ( ) disease resistance gene family in a wild banana. We identified 78 genes in the banana genome. Remarkably, seven formed a gene cluster in the distal part of chromosome 10, where resistance to Fusarium wilt caused by Foc race 1 has been previously mapped. Hence, we proposed these seven as resistance gene candidates (RGCs) for Fusarium wilt. We also identified seven other banana RGCs based on their close phylogenetic relationships with known LRR-RLP proteins. Moreover, phylogenetic analysis of the banana, rice, and LRR-RLP families revealed five major phylogenetic clades shared by these plant species. Finally, transcriptomic analysis of the gene family in plants treated with Foc race 1 or Foc TR4 showed the expression of several members of this family, and some of them were upregulated in response to these Foc races. Our study provides novel insights into the structure, distribution, evolution, and expression of the gene family in bananas as well as valuable RGCs that will facilitate the identification of disease resistance genes for the genetic improvement of this crop.
ISSN:2073-4425
2073-4425
DOI:10.3390/genes13040638