First-Trimester Fetal Hepatic Artery Examination for Adverse Outcome Prediction

To assess whether there are differences in first-trimester fetal hepatic artery flows depending on pregnancy outcomes. The prospective study conducted in 2012-2020 included 1841 fetuses from singleton pregnancies assessed during the routine first-trimester ultrasound examination (between 11- and 14-...

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Bibliographic Details
Published in:Journal of clinical medicine 2022-04, Vol.11 (8), p.2095
Main Authors: Czuba, Bartosz, Tousty, Piotr, Cnota, Wojciech, Borowski, Dariusz, Jagielska, Agnieszka, Dubiel, Mariusz, Fuchs, Anna, Fraszczyk-Tousty, Magda, Dzidek, Sylwia, Kajdy, Anna, Świercz, Grzegorz, Kwiatkowski, Sebastian
Format: Article
Language:English
Subjects:
Clinical medicine
Congenital diseases
Defects
Fetuses
Genetic disorders
Heart rate
Miscarriage
Patients
Pregnancy
Ultrasonic imaging
Veins & arteries
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Summary:To assess whether there are differences in first-trimester fetal hepatic artery flows depending on pregnancy outcomes. The prospective study conducted in 2012-2020 included 1841 fetuses from singleton pregnancies assessed during the routine first-trimester ultrasound examination (between 11- and 14-weeks' gestation). Also, each fetus was examined to determine their hepatic artery flows by measuring the artery's pulsatility index (HA-PI) and peak systolic velocity (HA-PSV). The fetuses that were classified as belonging to the adverse pregnancy outcome group (those with karyotype abnormalities and congenital heart defects) were characterized by a significantly lower HA-PI and higher HA-PSV compared to normal outcome fetuses. Hepatic artery flow assessment proved to be a very useful tool in predicting adverse pregnancy outcomes, in particular karyotype abnormalities and congenital heart defects.
ISSN:2077-0383
2077-0383
DOI:10.3390/jcm11082095