Can Complete Blood Count Picture Tell Us More About the Activity of Rheumatological Diseases?

Background: In clinical practice, distinguishing disease activity in patients with rheumatological illnesses is challenging. Objectives: We aimed to investigate clinical associations of hemogram-derived indices, namely: red cell distribution width (RDW), mean platelet volume (MPV), neutrophil-to-lym...

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Bibliographic Details
Published in:Clinical medicine insights. Arthritis and musculoskeletal disorders 2022, Vol.15, p.11795441221089182-11795441221089182
Main Authors: Taha, Sara I, Samaan, Sara F, Ibrahim, Rehab Ali, Moustafa, Nouran M, El-Sehsah, Eman M, Youssef, Mariam K
Format: Article
Language:English
Subjects:
Blood tests
Disease
Lymphocytes
Original Research
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Summary:Background: In clinical practice, distinguishing disease activity in patients with rheumatological illnesses is challenging. Objectives: We aimed to investigate clinical associations of hemogram-derived indices, namely: red cell distribution width (RDW), mean platelet volume (MPV), neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), lymphocyte-to-monocyte ratio (LMR), and systemic immune-inflammation index (SII) with disease activity in patients with rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), and ankylosing spondylitis (AS). Methods: In 250 patients with rheumatological disease and 100 healthy age-matched controls, we investigated disease activity scores and indicators and evaluated their association with hemogram-derived indices values. Results: Compared with the control group, RDW, MPV, and PLR significantly increased (P  .05). RDW and MPV showed significant changes (P 
ISSN:1179-5441
1179-5441
DOI:10.1177/11795441221089182