Multicenter survey of the changing in vitro antimicrobial susceptibilities of clinical isolates of Bacteroides fragilis group, Prevotella, Fusobacterium, Porphyromonas, and Peptostreptococcus species

In vitro surveys of antimicrobial resistance among clinically important anaerobes are an important source of information that can be used for clinical decisions in the choice of empiric antimicrobial therapy. This study surveyed the susceptibilities of 556 clinical anaerobic isolates from four large...

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Bibliographic Details
Published in:Antimicrobial agents and chemotherapy 2001-04, Vol.45 (4), p.1238-1243
Main Authors: ALDRIDGE, Kenneth E, ASHCRAFT, Deborah, CAMBRE, Karl, PIERSON, Carl L, JENKINS, Stephen G, ROSENBLATT, Jone
Format: Article
Language:English
Subjects:
Antibacterial agents
Antibiotics. Antiinfectious agents. Antiparasitic agents
Bacterial diseases
Bacterial Infections - microbiology
Bacteroides fragilis
Bacteroides fragilis - drug effects
Bacteroides fragilis - isolation & purification
Biological and medical sciences
ciprofloxacin
Drug Resistance, Microbial
Fusobacterium
Fusobacterium - drug effects
Fusobacterium - isolation & purification
Human bacterial diseases
Humans
imipenem
Infectious diseases
Medical sciences
meropenem
metronidazole
Microbial Sensitivity Tests
Miscellaneous
Peptostreptococcus
Peptostreptococcus - drug effects
Peptostreptococcus - isolation & purification
Pharmacology. Drug treatments
piperacillin
Porphyromonas
Porphyromonas - drug effects
Porphyromonas - isolation & purification
Prevotella
Prevotella - drug effects
Prevotella - isolation & purification
Species Specificity
Sulbactam
Susceptibility
taxobactam
Tazobactam
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Summary:In vitro surveys of antimicrobial resistance among clinically important anaerobes are an important source of information that can be used for clinical decisions in the choice of empiric antimicrobial therapy. This study surveyed the susceptibilities of 556 clinical anaerobic isolates from four large medical centers using a broth microdilution method. Piperacillin-tazobactam was the only antimicrobial agent to which all the isolates were susceptible. Similarly, imipenem, meropenem, and metronidazole were highly active (resistance,
ISSN:0066-4804
1098-6596
DOI:10.1128/AAC.45.4.1238-1243.2001