COVID-19 Pandemic Associated With Increased Self-reported Depressive Symptoms in Patients With Congenital Craniofacial Diagnoses

• Published in: The Cleft palate-craniofacial journal 2023-08, Vol.60 (8), p.949-955
• Main Authors: Huang, Kelly X., Oberoi, Michelle K., Caprini, Rachel M., Hu, Vivian J., Malapati, Sri Harshini, Mirzaie, Sarah, Bedar, Meiwand, Patel, Harsh, Lee, Justine C.
• Format: Article
• Language: English
• Subjects: Adolescent; Anxiety - epidemiology; Child; Child, Preschool; Coronaviruses; COVID-19; COVID-19 - epidemiology; COVID-19 - psychology; Depression - epidemiology; Humans; Longitudinal studies; Medical diagnosis; Original; Pandemics; Self Report
• ISSN: 1055-6656; 1545-1569; 1545-1569
• DOI: 10.1177/10556656221095715

Objective The current study investigated the influence of the coronavirus (COVID-19) pandemic on patients with congenital craniofacial diagnoses. Methods Patients (n = 66) with craniofacial diagnoses aged between 8 and 17 were prospectively evaluated with longitudinal psychosocial assessments using the anger, anxiety, depressive symptoms, and peer relationships instruments within the pediatric Patient-Reported Outcomes Measurement Information System (PROMIS). The COVID-19 cohort (n = 33) included patients with assessments within 2 years prior to the pandemic (t0) and during the pandemic (t1; March 2020 to March 2021). An age-matched comparison cohort (n = 33) with similar demographics and diagnoses included patients assessed twice over 3 years prior to the pandemic. Results All PROMIS measures were in the average range clinically for both groups across time points. However, the COVID-19 group reported a significant increase in depressive symptoms during the pandemic (t1) compared to pre-pandemic (t0) scores (48.2 ± 10.1 vs 44.3 ± 9.4, P = .04, d = −0.37), while the comparison group did not demonstrate any differences in psychosocial functioning between t0 and t1. For the COVID-19 cohort, only the pandemic timeframe (r = 0.21, P = .03) was significantly associated with increased depressive symptom scores, and no other sociodemographic or medical variables were associated with depressive symptoms. Conclusions Self-reported depressive symptoms increased during the COVID-19 pandemic in patients with congenital craniofacial diagnoses. Longitudinal studies are needed to elucidate whether such changes will be persistent or compound known variables associated with psychosocial functioning.