Mg3N2-assisted one-pot synthesis of 1,3-disubstituted imidazo[1,5-a]pyridine

A novel Mg3N2-assisted one-pot annulation strategy has been developed via cyclo-condensation reaction of 2-pyridyl ketones with alkyl glyoxylates or aldehydes, allowing the formation of imidazo[1,5-a]pyridines exclusively with an exellent yield.

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Bibliographic Details
Published in:RSC advances 2020-03, Vol.10 (20), p.11808-11815
Main Authors: Patil, Suhas G, Jadhav, Jagannath S, Sankpal, Sagar T
Format: Article
Language:English
Subjects:
Aldehydes
Chemical reactions
Chemistry
Ketones
Pyridines
Online Access:Get full text
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Description
Summary:A novel Mg3N2-assisted one-pot annulation strategy has been developed via cyclo-condensation reaction of 2-pyridyl ketones with alkyl glyoxylates or aldehydes, allowing the formation of imidazo[1,5-a]pyridines exclusively with an exellent yield.
ISSN:2046-2069
DOI:10.1039/c9ra10848c