PrEParing for NextGen: Cognitive Interviews to Improve Next Generation PrEP Modality Descriptions for Young Men Who have Sex with Men

Next generation PrEP formulations may circumvent factors that impede daily oral pre-exposure prophylaxis (PrEP) use among young men who have sex with men (YMSM). We conducted video-based cognitive interviews with 20 YMSM (age 16–24) recruited in the US Northeast to assess participants’ attitudes and...

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Bibliographic Details
Published in:AIDS and behavior 2022-06, Vol.26 (6), p.1956-1965
Main Authors: Biello, Katie B., Valente, Pablo K., Lin, Willey Y., Lodge II, William, Drab, Ryan, Hightow-Weidman, Lisa, da Silva, Daniel Teixeira, Mayer, Kenneth, Bauermeister, José A.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Cognition
Cognitive ability
Cognitive interviews
Descriptions
Disease prevention
Gays & lesbians
Health education
Health literacy
Health Psychology
HIV
HIV Infections - drug therapy
HIV Infections - prevention & control
Homosexuality, Male - psychology
Human immunodeficiency virus
Humans
Infectious Diseases
Male
Medicine
Medicine & Public Health
Men
Men who have sex with men
Mens health
Minority & ethnic groups
Minority groups
Original Paper
Pre-Exposure Prophylaxis
Prophylaxis
Public Health
Redundancy
Sexual and Gender Minorities
Teenagers
Young Adult
Young adults
Young men
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Summary:Next generation PrEP formulations may circumvent factors that impede daily oral pre-exposure prophylaxis (PrEP) use among young men who have sex with men (YMSM). We conducted video-based cognitive interviews with 20 YMSM (age 16–24) recruited in the US Northeast to assess participants’ attitudes and comprehension of written descriptions of next generation PrEP modalities. Participants were predominately racial/ethnic minorities and half used daily oral PrEP. We identified four main areas for improvement of descriptions: defining scientific terms and balancing medical jargon and casual language; referencing more established products to contextualize PrEP formulations (e.g., hormonal implants); ensuring clarity and reducing redundancy; and including imagery (e.g., rectal douche applicator). The refined descriptions serve as exemplar text that may be used in future studies examining YMSM’s preferences across next generation PrEP modalities. Accurate descriptions of next generation PrEP products strengthen measurement accuracy and can help roll-out products that become approved for clinical use.
ISSN:1090-7165
1573-3254
DOI:10.1007/s10461-021-03545-w