T1 hyperintensity in the spinal cord: A diagnostic marker of amyotrophic lateral sclerosis?

Amyotrophic Lateral Sclerosis (ALS) is a rare, devastating motor neuron disease characterized by the degeneration of upper and lower motor neurons causing muscular weakness, paralysis, and eventual death. MRI plays a supportive role in the diagnosis; its primary role is to exclude other clinical mim...

Full description

Saved in:
Bibliographic Details
Published in:Journal of clinical imaging science 2022-04, Vol.12, p.20, Article 20
Main Authors: Pai, Vivek, Trivedi, Chintan R, Pai, Bhujang, Swaminathan, Saravana K
Format: Article
Language:English
Subjects:
Case Report
Neuroradiology/Head and Neck Imaging
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c2692-544bcd3af023bdeec27193081d8f5dab88e510376c7863a7310dbfcb3f54decb3
cites cdi_FETCH-LOGICAL-c2692-544bcd3af023bdeec27193081d8f5dab88e510376c7863a7310dbfcb3f54decb3
container_end_page
container_issue
container_start_page 20
container_title Journal of clinical imaging science
container_volume 12
creator Pai, Vivek
Trivedi, Chintan R
Pai, Bhujang
Swaminathan, Saravana K
description Amyotrophic Lateral Sclerosis (ALS) is a rare, devastating motor neuron disease characterized by the degeneration of upper and lower motor neurons causing muscular weakness, paralysis, and eventual death. MRI plays a supportive role in the diagnosis; its primary role is to exclude other clinical mimics. Some of the imaging features associated with ALS include hypointense signal along the motor cortices on susceptibility or T2*-weighted imaging and hyperintensity along the corticospinal tracts (CST) within the cerebral hemispheres, brainstem, and spinal cord on the T2 weighted imaging. In this report, we discuss the value of T1 hyperintensity along the CST, especially in the spinal cord.
doi_str_mv 10.25259/JCIS_24_2022
format article
fullrecord <record><control><sourceid>pubmed_cross</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9062945</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>35510239</sourcerecordid><originalsourceid>FETCH-LOGICAL-c2692-544bcd3af023bdeec27193081d8f5dab88e510376c7863a7310dbfcb3f54decb3</originalsourceid><addsrcrecordid>eNpVkMtOwzAQRS0EolXpki3yDwT8TGIWoKriqUosKCsWlmM7jaGNIzsg5e-xaKnKbGY0jztHF4BzjC4JJ1xcPc-fXiVhkiBCjsCYYJ5nnIvieFcXHLMRmMb4gVIwwXLET8GIco4RoWIM3pcYNkNng2t720bXD9C1sG8sjJ1r1RpqH8w1nEHj1Kr1sXcablT4tAH6GqrN4PvguyZ116q3IR1EvbbBRxdvz8BJrdbRTnd5At7u75bzx2zx8vA0ny0yTXJBMs5YpQ1VdSKqjLWaFFhQVGJT1tyoqixtoqVFrosyp6qgGJmq1hWtOTM25Qm42ep2X9XGGm3bPoHILrhEOkivnPw_aV0jV_5bCpQTwXgSyLYCOoHHYOv9LUby12h5aHTavzh8uN_-s5X-ABqhe78</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>T1 hyperintensity in the spinal cord: A diagnostic marker of amyotrophic lateral sclerosis?</title><source>PubMed Central</source><creator>Pai, Vivek ; Trivedi, Chintan R ; Pai, Bhujang ; Swaminathan, Saravana K</creator><creatorcontrib>Pai, Vivek ; Trivedi, Chintan R ; Pai, Bhujang ; Swaminathan, Saravana K</creatorcontrib><description>Amyotrophic Lateral Sclerosis (ALS) is a rare, devastating motor neuron disease characterized by the degeneration of upper and lower motor neurons causing muscular weakness, paralysis, and eventual death. MRI plays a supportive role in the diagnosis; its primary role is to exclude other clinical mimics. Some of the imaging features associated with ALS include hypointense signal along the motor cortices on susceptibility or T2*-weighted imaging and hyperintensity along the corticospinal tracts (CST) within the cerebral hemispheres, brainstem, and spinal cord on the T2 weighted imaging. In this report, we discuss the value of T1 hyperintensity along the CST, especially in the spinal cord.</description><identifier>ISSN: 2156-7514</identifier><identifier>EISSN: 2156-5597</identifier><identifier>DOI: 10.25259/JCIS_24_2022</identifier><identifier>PMID: 35510239</identifier><language>eng</language><publisher>United States: Scientific Scholar</publisher><subject>Case Report ; Neuroradiology/Head and Neck Imaging</subject><ispartof>Journal of clinical imaging science, 2022-04, Vol.12, p.20, Article 20</ispartof><rights>2022 Published by Scientific Scholar on behalf of Journal of Clinical Imaging Science.</rights><rights>2022 Published by Scientific Scholar on behalf of Journal of Clinical Imaging Science 2022 Journal of Clinical Imaging Science</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2692-544bcd3af023bdeec27193081d8f5dab88e510376c7863a7310dbfcb3f54decb3</citedby><cites>FETCH-LOGICAL-c2692-544bcd3af023bdeec27193081d8f5dab88e510376c7863a7310dbfcb3f54decb3</cites><orcidid>0000-0001-7933-5994</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062945/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062945/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35510239$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pai, Vivek</creatorcontrib><creatorcontrib>Trivedi, Chintan R</creatorcontrib><creatorcontrib>Pai, Bhujang</creatorcontrib><creatorcontrib>Swaminathan, Saravana K</creatorcontrib><title>T1 hyperintensity in the spinal cord: A diagnostic marker of amyotrophic lateral sclerosis?</title><title>Journal of clinical imaging science</title><addtitle>J Clin Imaging Sci</addtitle><description>Amyotrophic Lateral Sclerosis (ALS) is a rare, devastating motor neuron disease characterized by the degeneration of upper and lower motor neurons causing muscular weakness, paralysis, and eventual death. MRI plays a supportive role in the diagnosis; its primary role is to exclude other clinical mimics. Some of the imaging features associated with ALS include hypointense signal along the motor cortices on susceptibility or T2*-weighted imaging and hyperintensity along the corticospinal tracts (CST) within the cerebral hemispheres, brainstem, and spinal cord on the T2 weighted imaging. In this report, we discuss the value of T1 hyperintensity along the CST, especially in the spinal cord.</description><subject>Case Report</subject><subject>Neuroradiology/Head and Neck Imaging</subject><issn>2156-7514</issn><issn>2156-5597</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNpVkMtOwzAQRS0EolXpki3yDwT8TGIWoKriqUosKCsWlmM7jaGNIzsg5e-xaKnKbGY0jztHF4BzjC4JJ1xcPc-fXiVhkiBCjsCYYJ5nnIvieFcXHLMRmMb4gVIwwXLET8GIco4RoWIM3pcYNkNng2t720bXD9C1sG8sjJ1r1RpqH8w1nEHj1Kr1sXcablT4tAH6GqrN4PvguyZ116q3IR1EvbbBRxdvz8BJrdbRTnd5At7u75bzx2zx8vA0ny0yTXJBMs5YpQ1VdSKqjLWaFFhQVGJT1tyoqixtoqVFrosyp6qgGJmq1hWtOTM25Qm42ep2X9XGGm3bPoHILrhEOkivnPw_aV0jV_5bCpQTwXgSyLYCOoHHYOv9LUby12h5aHTavzh8uN_-s5X-ABqhe78</recordid><startdate>20220427</startdate><enddate>20220427</enddate><creator>Pai, Vivek</creator><creator>Trivedi, Chintan R</creator><creator>Pai, Bhujang</creator><creator>Swaminathan, Saravana K</creator><general>Scientific Scholar</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-7933-5994</orcidid></search><sort><creationdate>20220427</creationdate><title>T1 hyperintensity in the spinal cord: A diagnostic marker of amyotrophic lateral sclerosis?</title><author>Pai, Vivek ; Trivedi, Chintan R ; Pai, Bhujang ; Swaminathan, Saravana K</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2692-544bcd3af023bdeec27193081d8f5dab88e510376c7863a7310dbfcb3f54decb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Case Report</topic><topic>Neuroradiology/Head and Neck Imaging</topic><toplevel>online_resources</toplevel><creatorcontrib>Pai, Vivek</creatorcontrib><creatorcontrib>Trivedi, Chintan R</creatorcontrib><creatorcontrib>Pai, Bhujang</creatorcontrib><creatorcontrib>Swaminathan, Saravana K</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of clinical imaging science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pai, Vivek</au><au>Trivedi, Chintan R</au><au>Pai, Bhujang</au><au>Swaminathan, Saravana K</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>T1 hyperintensity in the spinal cord: A diagnostic marker of amyotrophic lateral sclerosis?</atitle><jtitle>Journal of clinical imaging science</jtitle><addtitle>J Clin Imaging Sci</addtitle><date>2022-04-27</date><risdate>2022</risdate><volume>12</volume><spage>20</spage><pages>20-</pages><artnum>20</artnum><issn>2156-7514</issn><eissn>2156-5597</eissn><abstract>Amyotrophic Lateral Sclerosis (ALS) is a rare, devastating motor neuron disease characterized by the degeneration of upper and lower motor neurons causing muscular weakness, paralysis, and eventual death. MRI plays a supportive role in the diagnosis; its primary role is to exclude other clinical mimics. Some of the imaging features associated with ALS include hypointense signal along the motor cortices on susceptibility or T2*-weighted imaging and hyperintensity along the corticospinal tracts (CST) within the cerebral hemispheres, brainstem, and spinal cord on the T2 weighted imaging. In this report, we discuss the value of T1 hyperintensity along the CST, especially in the spinal cord.</abstract><cop>United States</cop><pub>Scientific Scholar</pub><pmid>35510239</pmid><doi>10.25259/JCIS_24_2022</doi><orcidid>https://orcid.org/0000-0001-7933-5994</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 2156-7514
ispartof Journal of clinical imaging science, 2022-04, Vol.12, p.20, Article 20
issn 2156-7514
2156-5597
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9062945
source PubMed Central
subjects Case Report
Neuroradiology/Head and Neck Imaging
title T1 hyperintensity in the spinal cord: A diagnostic marker of amyotrophic lateral sclerosis?
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-30T19%3A21%3A00IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-pubmed_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=T1%20hyperintensity%20in%20the%20spinal%20cord:%20A%20diagnostic%20marker%20of%20amyotrophic%20lateral%20sclerosis?&rft.jtitle=Journal%20of%20clinical%20imaging%20science&rft.au=Pai,%20Vivek&rft.date=2022-04-27&rft.volume=12&rft.spage=20&rft.pages=20-&rft.artnum=20&rft.issn=2156-7514&rft.eissn=2156-5597&rft_id=info:doi/10.25259/JCIS_24_2022&rft_dat=%3Cpubmed_cross%3E35510239%3C/pubmed_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c2692-544bcd3af023bdeec27193081d8f5dab88e510376c7863a7310dbfcb3f54decb3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_id=info:pmid/35510239&rfr_iscdi=true