A ratiometric and colorimetric probe for detecting Hg2+ based on naphthalimide–rhodamine and its staining function in cell imaging

In this work, a rhodamine derivative was developed as a colorimetric and ratiometric fluorescent probe for Hg2+. It exhibited a highly sensitive fluorescence response toward Hg2+. Importantly, studies revealed that the probe could be used for ratiometric detection of Hg2+, with a low detection limit...

Full description

Saved in:
Bibliographic Details
Published in:RSC advances 2019-01, Vol.9 (21), p.11664-11669
Main Authors: Wang, Yuesong, Ding, Haichang, Wang, Shuai, Fan, Congbin, Tu, Yayi, Liu, Gang, Pu, Shouzhi
Format: Article
Language:English
Subjects:
Chemistry
Colorimetry
Fluorescent indicators
Mercury (metal)
NMR
Nuclear magnetic resonance
Rhodamine
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In this work, a rhodamine derivative was developed as a colorimetric and ratiometric fluorescent probe for Hg2+. It exhibited a highly sensitive fluorescence response toward Hg2+. Importantly, studies revealed that the probe could be used for ratiometric detection of Hg2+, with a low detection limit of 0.679 μM. The mechanism of Hg2+ detection using compound 1 was confirmed by ESI-MS, 1H NMR, and HPLC. Upon the addition of Hg2+, the rhodamine receptor was induced to be in the ring-opening form via an Hg2+-promoted hydrolysis of rhodamine hydrazide to rhodamine acid. In addition to Hg2+ detection, the naphthalimide–rhodamine compound was proven to be effective in cell imaging.
ISSN:2046-2069
DOI:10.1039/c9ra01459d