Exploration of the Impact of Combining Risk Phenotypes on the Likelihood of Alcohol Problems in Young Adults

We tested the hypothesis that high novelty seeking (NS-an externalizing trait), sweet-liking (SL-a phenotype that may reflect processing of hedonic stimuli) and initial insensitivity to the impairing effects of alcohol (SRE-A) act independently and synergistically to increase the likelihood of havin...

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Bibliographic Details
Published in:Alcohol and alcoholism (Oxford) 2022-05, Vol.57 (3), p.357-363
Main Authors: Kampov-Polevoy, Alexei, Bobashev, Georgiy, Garbutt, James C
Format: Article
Language:English
Subjects:
Alcohol-Related Disorders
Alcoholism - diagnosis
Alcoholism - epidemiology
Alcoholism - genetics
Humans
Phenotype
Risk Factors
Taste
Young Adult
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Summary:We tested the hypothesis that high novelty seeking (NS-an externalizing trait), sweet-liking (SL-a phenotype that may reflect processing of hedonic stimuli) and initial insensitivity to the impairing effects of alcohol (SRE-A) act independently and synergistically to increase the likelihood of having alcohol-related problems in young adults. A sample of 145 young adults, ages 18-26, balanced for gender and alcohol use disorders identification test (AUDIT) scores
ISSN:0735-0414
1464-3502
DOI:10.1093/alcalc/agab049