Relationship between disease impact scores and C-reactive protein/albumin ratio in patients with psoriatic arthritis

• Published in: Croatian Medical Journal 2022-04, Vol.63 (2), p.141-147
• Main Authors: Duran, Tugba Izci, Pamukcu, Melih
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Arthritis, Psoriatic; C-reactive protein; C-Reactive Protein - analysis; Cross-Sectional Studies; Development and progression; Female; Health aspects; Humans; Male; Measurement; Middle Aged; Prognosis; Psoriatic arthritis; Retrospective Studies; Serum albumin
• ISSN: 0353-9504; 1332-8166
• DOI: 10.3325/cmj.2022.63.141

To evaluate the relationships between the C-reactive protein (CRP)/albumin ratio (CAR), neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), and Disease Activity in Psoriatic Arthritis (DAPSA) and Psoriatic Arthritis Impact of Disease 12-item-questionnaire (PsAID-12) scores in patients with psoriatic arthritis (PsA). This cross-sectional study involved 160 (121 female) patients with PsA who were >18 years old and treated in the rheumatology clinic of Dışkapı Yıldırım Beyazıt Education and Research Hospital between January 2020 and January 2021. Demographic and clinical data, PsAID-12 and DAPSA scores, CRP, erythrocyte sedimentation rate (ESR), albumin level, neutrophil, lymphocyte, and platelet counts were recorded. The mean age was 46.49±11.12 years; median (min-max) disease duration was 2 years (0.5-34). The PsAID score was ≥4 (high disease impact) in 74.4% of patients. Patients with high disease impact had significantly higher CRP, ESR, CAR, NLR, PLR, neutrophil counts, and DAPSA scores (P