Correlation of Intraprocedural and Follow Up Parameters for Mitral Regurgitation Grading after Percutaneous Edge-to-Edge Repair

Background: There is no consensus on the best intraprocedural parameter to evaluate residual mitral regurgitation (MR) after transcatheter edge-to-edge mitral repair (TEER). Thus, our aim was to evaluate the predictive value of different MR parameters from intraprocedural transesophageal echocardiog...

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Bibliographic Details
Published in:Journal of clinical medicine 2022-04, Vol.11 (9), p.2276
Main Authors: Pozo Osinalde, Eduardo, Salinas Gallegos, Alejandra, Gordillo, Ximena, Nombela Franco, Luis, Marcos-Alberca, Pedro, Mahía, Patricia, Tirado-Conte, Gabriela, Gómez de Diego, José Juan, Jiménez Quevedo, Pilar, Fernández-Ortíz, Antonio, Pérez-Villacastín, Julián, de Agustín Loeches, Jose Alberto
Format: Article
Language:English
Subjects:
Cardiovascular disease
Clinical medicine
Etiology
Heart
Medical records
Mortality
Pulmonary arteries
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Summary:Background: There is no consensus on the best intraprocedural parameter to evaluate residual mitral regurgitation (MR) after transcatheter edge-to-edge mitral repair (TEER). Thus, our aim was to evaluate the predictive value of different MR parameters from intraprocedural transesophageal echocardiogram (TEE) for grading in consecutive transthoracic echocardiogram (TTE) during the follow up. Methods: All the consecutive patients who underwent TEER with MitraClip between 2010 and 2020 in our center were considered. TEE-derived immediate postprocedural MR parameters were reassessed to blindly compare them with follow up MR grading in sequential TTE. Results: We finally included 88 patients (64.8% males; 76 ± 10 years-old). Significant MR was detected in 14.3% of the cases at 6 months, in similar proportion than at postprocedural at 1 month. Among all the intraprocedural TEE quantitative parameters only additive and maximum VC were associated with significant MR persistence. Moreover, on ROC analysis maximum VC demonstrated an excellent discriminatory power (AUC 0.96; p < 0.001) to identify MR ≥ III at 6 months. Thus, a cut-off point of 0.45 cm demonstrated 88% sensitivity and 89% specificity. Conclusion: Among intraprocedural TEE parameters to evaluate residual MR in TEER, maximum and additive VC were the most reliable to predict persistence of significant insufficiency.
ISSN:2077-0383
2077-0383
DOI:10.3390/jcm11092276