Vulvar Cancer: 2021 Revised FIGO Staging System and the Role of Imaging

Vulvar cancer is a rare gynecological malignancy. It constitutes 5-8% of all gynecologic neoplasms, and squamous cell carcinoma is the most common variant. This article aims to review the etiopathogenesis revised 2021 International Federation of Gynecology and Obstetrics (FIGO) classification and em...

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Bibliographic Details
Published in:Cancers 2022-04, Vol.14 (9), p.2264
Main Authors: Virarkar, Mayur, Vulasala, Sai Swarupa, Daoud, Taher, Javadi, Sanaz, Lall, Chandana, Bhosale, Priya
Format: Article
Language:English
Subjects:
Biopsy
Cell cycle
Clitoris
Cyclin-dependent kinases
Genital cancers
Gynecology
Human papillomavirus
Kinases
Lymph nodes
Lymphatic system
Malignancy
Metastases
Mutation
Obstetrics
Proteins
Review
Squamous cell carcinoma
Tumors
Vagina
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Summary:Vulvar cancer is a rare gynecological malignancy. It constitutes 5-8% of all gynecologic neoplasms, and squamous cell carcinoma is the most common variant. This article aims to review the etiopathogenesis revised 2021 International Federation of Gynecology and Obstetrics (FIGO) classification and emphasize imaging in the staging of vulvar cancer. The staging has been regulated by FIGO since 1969 and is subjected to multiple revisions. Previous 2009 FIGO classification is limited by the prognostic capability, which prompted the 2021 revisions and issue of a new FIGO classification. Although vulvar cancer can be visualized clinically, imaging plays a crucial role in the staging of the tumor, assessing the tumor extent, and planning the management. In addition, sentinel lymph node biopsy facilitates the histopathological staging of the draining lymph node, thus enabling early detection of tumor metastases and better survival rates.
ISSN:2072-6694
2072-6694
DOI:10.3390/cancers14092264