Calcium chloride dihydrate supplementation at ICSI improves fertilization and pregnancy rates in patients with previous low fertilization: a retrospective paired treatment cycle study

Purpose To determine if 5mM calcium chloride dihydrate supplementation of the Polyvinylpyrrolidone (PVP) media at the time of ICSI (ICSI-Ca) improves fertilization, utilization, and clinical pregnancy rates compared to ICSI alone, particularly in patients with a history of low fertilization (

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Bibliographic Details
Published in:Journal of assisted reproduction and genetics 2022-05, Vol.39 (5), p.1055-1064
Main Authors: Popkiss, Sophie, Horta, Fabrizzio, Vollenhoven, Beverley, Green, Mark P., Zander-Fox, Deirdre
Format: Article
Language:English
Subjects:
Assisted Reproduction Technologies
Calcium
Calcium Chloride
Dietary Supplements
Embryos
Female
Fertilization
Fertilization in Vitro
Gynecology
Human Genetics
Humans
Medicine
Medicine & Public Health
Oocytes
Patients
Polyvinylpyrrolidone
Pregnancy
Pregnancy Rate
Reproductive Medicine
Retrospective Studies
Sperm Injections, Intracytoplasmic
Supplements
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Summary:Purpose To determine if 5mM calcium chloride dihydrate supplementation of the Polyvinylpyrrolidone (PVP) media at the time of ICSI (ICSI-Ca) improves fertilization, utilization, and clinical pregnancy rates compared to ICSI alone, particularly in patients with a history of low fertilization (
ISSN:1058-0468
1573-7330
DOI:10.1007/s10815-022-02407-1