Coupling Lipid Labeling and Click Chemistry Enables Isolation of Extracellular Vesicles for Noninvasive Detection of Oncogenic Gene Alterations (Adv. Sci. 14/2022)

Extracellular Vesicle In article number 2105853 by Renjun Pei, Shaohua Lu, Hsian‐Rong Tseng, Yazhen Zhu, and co‐workers, an efficient, convenient, and rapid extracellular vesicle (EV) enrichment platform called EV Click Beads is developed by combining lipid labelling and click chemistry‐based captur...

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Published in:Advanced science 2022-05, Vol.9 (14), p.n/a
Main Authors: Sun, Na, Tran, Benjamin V., Peng, Zishan, Wang, Jing, Zhang, Ceng, Yang, Peng, Zhang, Tiffany X., Widjaja, Josephine, Zhang, Ryan Y., Xia, Wenxi, Keir, Alexandra, She, Jia‐Wei, Yu, Hsiao‐hua, Shyue, Jing‐Jong, Zhu, Hongguang, Agopian, Vatche G., Pei, Renjun, Tomlinson, James S., Toretsky, Jeffrey A, Jonas, Steven J., Federman, Noah, Lu, Shaohua, Tseng, Hsian‐Rong, Zhu, Yazhen
Format: Article
Language:English
Subjects:
Extracellular vesicles
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Summary:Extracellular Vesicle In article number 2105853 by Renjun Pei, Shaohua Lu, Hsian‐Rong Tseng, Yazhen Zhu, and co‐workers, an efficient, convenient, and rapid extracellular vesicle (EV) enrichment platform called EV Click Beads is developed by combining lipid labelling and click chemistry‐based capturing. EV Click Beads provides a non‐invasive diagnostic solution for detection of disease status and monitoring treatment response for cancer patients, including Ewing sarcoma, the second most common type of bone cancer in children.
ISSN:2198-3844
2198-3844
DOI:10.1002/advs.202270091