Using a Biosensor Based on Surface-Enhanced Raman Scattering to Identify Influenza Viruses in Biological Fluids

Biosensors based on the effect of surface-enhanced Raman scattering obtained on silver nanoclusters modified with DNA aptamers allow viruses to be detected with high sensitivity. However, measurements in biological media are complicated by the nonspecific sorption of biomolecules on silver. Conditio...

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Bibliographic Details
Published in:Bulletin of the Russian Academy of Sciences. Physics 2022-04, Vol.86 (4), p.434-437
Main Authors: Zhdanov, G. A., Gribanyov, D. A., Gambaryan, A. S., Kukushkin, V. I., Zavyalova, E. G.
Format: Article
Language:English
Subjects:
Biomolecules
Biosensors
Hadrons
Heavy Ions
Nanoclusters
Nuclear Physics
Physics
Physics and Astronomy
Raman spectra
Sorption
Viruses
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Summary:Biosensors based on the effect of surface-enhanced Raman scattering obtained on silver nanoclusters modified with DNA aptamers allow viruses to be detected with high sensitivity. However, measurements in biological media are complicated by the nonspecific sorption of biomolecules on silver. Conditions for preparing samples of biological fluids that allow the nonspecific sorption of biomolecules to be nullified are studied.
ISSN:1062-8738
1934-9432
DOI:10.3103/S1062873822040293