Burden of cardiovascular dysfunction and outcome among term newborns having birth asphyxia

To find out the burden of cardiovascular dysfunction and outcome among term newborns having birth asphyxia. This prospective observational study was conducted at The Department of Neonatology, Children's Hospital and The Institute of Child Health, Multan from August 2020 to March 2021.A total o...

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Bibliographic Details
Published in:Pakistan journal of medical sciences 2022-03, Vol.38 (4Part-II), p.883-887
Main Authors: Shakir, Waqas, Abdur-Rehman, Arshad, M Sohail, Fatima, Nazia
Format: Article
Language:English
Subjects:
Apgar score
Asphyxia
Asphyxia neonatorum
Birth weight
Cesarean section
Developing countries
Electrocardiography
Gestational age
Health aspects
Hypotension
Hypoxia
India
Infants (Newborn)
Ischemia
LDCs
Mortality
Neonatology
Original
Pulmonary hypertension
Suffocation
Vagina
Ventilators
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Summary:To find out the burden of cardiovascular dysfunction and outcome among term newborns having birth asphyxia. This prospective observational study was conducted at The Department of Neonatology, Children's Hospital and The Institute of Child Health, Multan from August 2020 to March 2021.A total of 171 term newborns having asphyxia were enrolled. Detailed history along with clinical and physical examination were done at the time of admission at Neonatal Intensive Care Unit (NICU). All neonates were followed up for duration of 14 days following birth. Echocardiographic patterns as well as electrocardiography grading were described among neonates with cardiovascular abnormalities. Out of a total of 171 neonates, there were 94 (55.0%) male and 77 (45.0%) female. Lowe segment cesarean section was the mode of delivery in 72 (42.1%) while normal vaginal delivery was noted in 99 (57.9%). Mean gestational age was noted to be 38.3±1.8 weeks. Mean birth weight was calculated to be 2574.10±122.30 grams. Cardiovascular dysfunction was noted among 60 (35.1%) neonates as exhibited by the use of inotropes while abnormal ECHO was observed in 52 (30.4%), abnormal ECG in 27 (15.8%) and elevated CK-MB in 31 (18.1%). A total of 29 (17.0%) asphyxiated neonates died while among 60 asphyxiated neonates with cardiovascular dysfunction, 23 (38.3%) died and all remaining survived and discharged (p
ISSN:1682-024X
1681-715X
DOI:10.12669/pjms.38.4.5160