Postdischarge outcomes of COVID-19 patients from South Asia: a prospective study

Coronavirus disease 2019 (COVID-19) may cause clinical manifestations that last for weeks or months after hospital discharge. The manifestations are heterogeneous and vary in their frequency. Their multisystem nature requires a holistic approach to management. There are sparse data from the South As...

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Published in:Transactions of the Royal Society of Tropical Medicine and Hygiene 2022-12, Vol.116 (12), p.1129-1137
Main Authors: Abeysuriya, Visula, Seneviratne, Suranjith L, De Silva, Arjuna P, Mowjood, Riaz, Mowjood, Shazli, de Silva, Thushara, de Mel, Primesh, de Mel, Chandima, Wijesinha, R S, Fernando, Amitha, de Mel, Sanjay, Chandrasena, Lal
Format: Article
Language:English
Subjects:
Aftercare
COVID-19 - epidemiology
COVID-19 Vaccines
Humans
Male
Original
Patient Discharge
Prospective Studies
SARS-CoV-2
Sri Lanka - epidemiology
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Summary:Coronavirus disease 2019 (COVID-19) may cause clinical manifestations that last for weeks or months after hospital discharge. The manifestations are heterogeneous and vary in their frequency. Their multisystem nature requires a holistic approach to management. There are sparse data from the South Asian region on the outcomes of hospital-discharged COVID-19 patients. We assessed the posthospital discharge outcomes of a cohort of Sri Lankan COVID-19 patients and explored the factors that influenced these outcomes. Data were prospectively collected from patients who were discharged following an admission to the Nawaloka Hospital, Sri Lanka with COVID-19 from March to June 2021. At discharge, their demographic, clinical and laboratory findings were recorded. The patients were categorised as having mild, moderate and severe COVID-19, based on the Sri Lanka Ministry of Health COVID-19 guidelines. Following discharge, information on health status, complications and outcomes was collected through clinic visits and preplanned telephone interviews. A validated (in Sri Lanka) version of the Short Form 36 health survey questionnaire (SF-36) was used to assess multi-item dimensions health status of the patients at 1, 2 and 3 mo postdischarge. We collected data on 203 patients (male, n=111 [54.7%]). The level of vaccination was significantly associated with disease severity (p
ISSN:0035-9203
1878-3503
DOI:10.1093/trstmh/trac039