Safety and Adequacy of Ultrasound-Guided Percutaneous Renal Biopsy in Children: A Single-Center Experience

Background Ultrasound-guided percutaneous renal biopsy (PCRB) is a commonly used technique to obtain renal tissue for histopathological diagnosis in children and adolescents. The objectives of this study include determining the indications for renal biopsy, documenting the safety and efficacy of ult...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2022-04, Vol.14 (4), p.e24452-e24452
Main Authors: Bux, Kausar Illahi, Moorani, Khemchand N, Qureshi, Hina, Kumari, Usha, Khan, Faheemullah, Farooq, Faryal, Abbas, Fakhar, Aman, Muhammad, Sahito, Abdul Moiz, Musharraff, Faisal, Alam, Muhammad Sami
Format: Article
Language:English
Subjects:
Automation
Biopsy
Blood tests
General anesthesia
Hematoma
Hematuria
Histopathology
Kidney diseases
Kidneys
Lupus
Nephrology
Patients
Pediatrics
Purpura
Radiology
Steroids
Ultrasonic imaging
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Summary:Background Ultrasound-guided percutaneous renal biopsy (PCRB) is a commonly used technique to obtain renal tissue for histopathological diagnosis in children and adolescents. The objectives of this study include determining the indications for renal biopsy, documenting the safety and efficacy of ultrasound-guided PCRB, and documenting its complications along with histopathological findings in children. Methodology The Ethical Review Committee approved this cross-sectional study. Data of all children with either nephrotic or nephritic syndrome from January 2017 to September 2020 (at The Kidney Center Post Graduate Training Institute Karachi) who underwent ultrasound-guided PCRB were collected and analyzed. An ultrasonic examination was performed both before and after the biopsy. Results During the research period, 104 individuals underwent PCRB. The average age of the children biopsied was 7.44 ± 4.12 years (range = 1-17 years). The most prevalent reason for biopsy was nephrotic syndrome. Almost 94% of PCRBs were effective. Post-biopsy complications were detected in 16 cases, with peri-nephric hematoma being the most prevalent. Conclusions In children, ultrasound-guided PCRB can safely be performed under sedation in experienced hands with an automated biopsy gun needle. The use of real-time ultrasound guidance as well as the automated biopsy gun ensures good outcomes.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.24452